DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d2 and CYP714A2

DIOPT Version :9

Sequence 1:	NP_001284806.1	Gene:	Cyp4d2 / 31192	FlyBaseID:	FBgn0011576	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_197872.1	Gene:	CYP714A2 / 832559	AraportID:	AT5G24900	Length:	525	Species:	Arabidopsis thaliana

Alignment Length:	535	Identity:	128/535 - (23%)
Similarity:	228/535 - (42%)	Gaps:	114/535 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 WRRRGN----GILPGPRPLPFLGNLLMYRGLDPE----------------QIMDFVKKNQRKYGR 67
            ||.|.:    |: .||.|..|.||:...:.:..|                .:.......:::|||
plant    36 WRMRRSLKLQGV-KGPPPSIFNGNVSEMQRIQSEAKHCSGDNIISHDYSSSLFPHFDHWRKQYGR 99

  Fly    68 LY--------RVWILH-----QLAVFSTDPRDIEFVLSSQQHITKNNLYKLLNCWLGDGLLMSTG 119
            :|        .::|.|     :|:..:|      ..|....||||.     ||..||:|::.|.|
plant   100 IYTYSTGLKQHLYINHPEMVKELSQTNT------LNLGRITHITKR-----LNPILGNGIITSNG 153

  Fly   120 RKWHGRRKIITPTFHFKILEQFVEIFDQQSAVMV---EQLQSRADGM-TPINIFPVICLTALDII 180
            ..|..:|:||...|....::..|.:..:.:..|:   |::..|...| ..|.:...:...:.|:|
plant   154 PHWAHQRRIIAYEFTHDKIKGMVGLMVESAMPMLNKWEEMVKRGGEMGCDIRVDEDLKDVSADVI 218

  Fly   181 AETAMGTKINAQKNPNLPYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQPTEAKRQDKAIKVMHD 245
            |:...|:..:..|    .....:.|:...:.||.:        :||                .:.
plant   219 AKACFGSSFSKGK----AIFSMIRDLLTAITKRSV--------LFR----------------FNG 255

  Fly   246 FTENIIRERRE----------TLVNNSKETTPEEEVNFLGQKRRMALLDVLLQSTIDGAPLSDED 300
            ||:.:...::.          .|.::..||..|.|:......::     .|:|..::||..|.:.
plant   256 FTDMVFGSKKHGDVDIDALEMELESSIWETVKEREIECKDTHKK-----DLMQLILEGAMRSCDG 315

  Fly   301 -----------IREEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVT 354
                       :.:...:..|.|||:|..::|:||..::.:|..|.:::.||   |...:.....
plant   316 NLWDKSAYRRFVVDNCKSIYFAGHDSTAVSVSWCLMLLALNPSWQVKIRDEI---LSSCKNGIPD 377

  Fly   355 LRDLGELKFMENVIKESLRLHPPVPMIGRWFAEDVEIRGKHIPAGTNFTMGIFVLLRDPEYFESP 419
            ...:..||.:..||:|::||:||.|::||..::|:.:....:|.|......|..|.||||.: .|
plant   378 AESIPNLKTVTMVIQETMRLYPPAPIVGREASKDIRLGDLVVPKGVCIWTLIPALHRDPEIW-GP 441

  Fly   420 D--EFRPERFDADVPQI--HPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLPLGPEPR 480
            |  :|:||||...:.:.  :|.:||||..|||.|:|:.|.|:|:|..||.::..|. ..|.|..:
plant   442 DANDFKPERFSEGISKACKYPQSYIPFGLGPRTCVGKNFGMMEVKVLVSLIVSKFS-FTLSPTYQ 505

  Fly   481 HSMN--IVLRSANGV 493
            ||.:  :::...:||
plant   506 HSPSHKLLVEPQHGV 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_001284806.1	p450	32..495	CDD:278495	124/522 (24%)
CYP714A2	NP_197872.1	p450	37..524	CDD:299894	127/534 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.960