DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4d2 and CYP96A13

DIOPT Version :9

Sequence 1:	NP_001284806.1	Gene:	Cyp4d2 / 31192	FlyBaseID:	FBgn0011576	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_195910.1	Gene:	CYP96A13 / 831752	AraportID:	AT5G02900	Length:	480	Species:	Arabidopsis thaliana

Alignment Length:	539	Identity:	121/539 - (22%)
Similarity:	225/539 - (41%)	Gaps:	124/539 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LVAFATLLLWDFLWRRRGN----GILPGPRPLPFLGNLLMYRGLDPEQIMDF---VKKNQRKYGR 67
            :..|..::|..||    ||    |:|||         ||    |:..:|.||   |.:|......
plant    11 IAIFCFIILHFFL----GNWPVLGMLPG---------LL----LEFHRIYDFSVEVLENSDLTFP 58

  Fly    68 LYRVWILHQLAVFSTDPRDIEFVLSSQ-QHITKNNLYKLLNCWLGDGLLMSTGRK-WHGRRKIIT 130
            ....|......:|:.||.:|..::||. .:.||...:|.:....|||:|.:...: |...:|
plant    59 FKGPWFTGMDMLFTVDPTNIHHIMSSNFSNYTKGPDFKQVFDVFGDGILTTDDSELWKNLKK--- 120

  Fly   131 PTFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIAETAMGT---KINAQ 192
                             .|.||:.....:.:| |.:::..|......|....|..|:   :..:.
plant   121 -----------------ASLVMLNHQGFQKNG-TVVDLQDVFKRFMFDTTLVTVTGSADPRSLSI 167

  Fly   193 KNPNLPYVQAVNDVTNILIKRFIHAWQRVDW-IFRLTQPTEAKRQDKAIKVMHDFTENIIRERRE 256
            :.|.:.:.:|::.|...::.|  |...|:.| :.:.....:.|:..||...::......|.|:||
plant   168 EMPEVEFAKALDHVGEGIMHR--HVRPRLLWKLQKCVGFGQEKKFSKADATLNQACAKYILEKRE 230

  Fly   257 TL--------VNNSK-----------ETTPEEEVNFLGQKRRMALLDVLLQSTIDGAPLSDEDIR 302
            ..        .|.|:           :||..|.:|                      |..|:.:|
plant   231 ETRSQGFDYHSNGSESEDILTYHIKIDTTKYELLN----------------------PSDDKFLR 273

  Fly   303 EEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVL-GEDRKSPVTLRDLGELKFMEN 366
            :.:..|:..|.|||.||:::..:.:..:|:|..:::|||.... |:::.|...:..|..|.::..
plant   274 DTILAFVLAGRDTTASALTWFFWLLLENPQVVTKIRQEINTSNGGQEKPSCEPMEYLNNLVYLHG 338

  Fly   367 VIKESLRLHPPVPMIGRWFAEDVEIRGKHIPAG--TNFTMGIFVLL-----RDPEYFESPDEFRP 424
            .:.|::||:||||     |.....|:...:|:|  .:.:|.|.:.:     ....:.|...||:|
plant   339 ALYEAMRLYPPVP-----FERMSPIKPDVLPSGHKVDSSMKILIFIYALGRMRAVWGEDASEFKP 398

  Fly   425 ERFDADVPQIH---PYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFEL--------LPLGPE 478
            ||:.::...:.   .:.::.|:||||:|||::.||..||..|.::|:::::        :...|.
plant   399 ERWLSETTSLRHEPSFKFLAFNAGPRSCIGKQLAMTLMKIVVVEILQNYDIKVVKGQKKIEPAPG 463

  Fly   479 PRHSMNIVLRSANGVHLGL 497
            |      :||..:|:.:.|
plant   464 P------ILRMKHGLRVTL 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_001284806.1	p450	32..495	CDD:278495	112/509 (22%)
CYP96A13	NP_195910.1	p450	1..479	CDD:299894	121/539 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010