DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4d2 and CYP94D2

DIOPT Version :9

Sequence 1:	NP_001284806.1	Gene:	Cyp4d2 / 31192	FlyBaseID:	FBgn0011576	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_191222.1	Gene:	CYP94D2 / 824830	AraportID:	AT3G56630	Length:	499	Species:	Arabidopsis thaliana

Alignment Length:	546	Identity:	133/546 - (24%)
Similarity:	237/546 - (43%)	Gaps:	103/546 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VLLLVAFATLLLWDFLWRRRGNGILPGPRPLPFLGNL-----LMYRGLD---------PEQIMDF 57
            ::.|:.|..::.:.|..:...:..  |.:..|.:|:|     ..:|.||         |.|...|
plant     6 LISLLCFPIVIFFIFFPKNSSSEF--GFKSYPIVGSLPGLVNNRHRFLDWTVETLSRCPTQTAIF 68

  Fly    58 VKKNQRKYGRLYRVWILHQLAVFSTDPRDIEFVLSSQ-QHITKNNLY-KLLNCWLGDGLLMSTGR 120
                 |:.|:|.        .|.:.:|.::|::|.:: :...|...: .:|..:||.|:..|.|.
plant    69 -----RRPGKLQ--------FVMTANPANVEYMLKTKFESFPKGERFISILEDFLGRGIFNSDGE 120

  Fly   121 KWHGRRKIITPTFHFKILEQFV--EIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIAET 183
            .|..:||..:..|..|.|..||  .:..:.:..:|..|...|.....|::..::...|.|.|.:.
plant   121 MWWKQRKTASYEFSTKSLRDFVMSNVTVEINTRLVPVLAEAATNGKLIDLQDILERFAFDNICKL 185

  Fly   184 AMGTK---INAQKNPNLPYVQAVNDVTNILIKRF----IHAWQRVDWIFRLTQPTEAKRQDKAIK 241
            |....   :.......:.::||......|:.:||    .::|:    |.:.......:...::|.
plant   186 AFNVDSACLGDDGAAGVNFMQAFETAATIISQRFQSVISYSWK----IKKKLNIGSERVLRESIM 246

  Fly   242 VMHDFTENIIRERRET-LVNNSKET-----TPEEEVNFLGQKRRMALLDVLLQSTIDGAPLSDED 300
            ::|.|.:.|:|.|.|. .|::.||.     ..:||:|                        |.|.
plant   247 IVHKFADEIVRNRIEQGKVSDHKEDLLSRFISKEEMN------------------------SPEI 287

  Fly   301 IREEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQE---IRDVLGEDRKSPVTLRDLGELK 362
            :|:.|.:|:..|.|||:||:|:..:.:|.||||:.::.||   ||:..|:.........||..:.
plant   288 LRDIVISFILAGRDTTSSALSWFFWLLSMHPEVKDKILQELNSIRERTGKRIGEVYGFEDLKLMN 352

  Fly   363 FMENVIKESLRLHPPVPMIGRWFAEDVEIRGKHIPAGT-----------NFTMGIFVLLRDPEYF 416
            ::...|.|||||:||||:.....|||     ..:|.||           .:.||    ..:..:.
plant   353 YLHAAITESLRLYPPVPVDTMSCAED-----NVLPDGTFIGKDWGISYNAYAMG----RMESIWG 408

  Fly   417 ESPDEFRPERF----DADVPQIHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLPLGP 477
            :..|.|.|||:    :......:||.:..|.||||.|:|::.|.::|||.|:.:|..|.:...|.
plant   409 KDCDRFDPERWIDETNGGFRGENPYKFPAFHAGPRMCLGKEMAYIQMKSIVAAVLERFVVEVPGK 473

  Fly   478 E--PRHSMNIVLRSANGVHLGLKPRA 501
            :  |...|::.||...|:::.::.|:
plant   474 KERPEILMSVTLRIRGGLNVRVQERS 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_001284806.1	p450	32..495	CDD:278495	129/513 (25%)
CYP94D2	NP_191222.1	p450	52..499	CDD:299894	123/496 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920