DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d2 and CYP94B2

DIOPT Version :9

Sequence 1:	NP_001284806.1	Gene:	Cyp4d2 / 31192	FlyBaseID:	FBgn0011576	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_566155.1	Gene:	CYP94B2 / 821263	AraportID:	AT3G01900	Length:	496	Species:	Arabidopsis thaliana

Alignment Length:	524	Identity:	123/524 - (23%)
Similarity:	224/524 - (42%)	Gaps:	115/524 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLGVVGVLLLVAFATLLLWDFLWRRRGNGILPGPRPLPFLGNLLMYRGLDPEQIMDFVKKNQRKY 65
            :|.:|.|||||:....:::..   |...     |:..|.:|.|:.:. .:..:::|:       |
plant     7 ILLLVLVLLLVSAGKHVIYSC---RNST-----PKTYPVIGCLISFY-TNRNRLLDW-------Y 55

  Fly    66 GRLY-----RVWILHQLA----VFSTDPRDIEFVLSSQ-QHITKNNLY-KLLNCWLGDGLLMSTG 119
            ..|.     |..::.:||    |.:.:|.::|::|.:. .:..|...: ::|..:||:|:....|
plant    56 TELLTESPSRTVVIRRLAARRTVVTANPSNVEYILKTNFDNYPKGKPFTEILGDFLGNGIFNVDG 120

  Fly   120 RKWHGRRKIITPTFHFKILEQFVEIF-DQQSAVMVEQLQSRADGMTPINI--------FPVICLT 175
            ..|..:|::.|..|..|.|.::|.:. ::....::..|.:.|:...|.::        |.::|:.
plant   121 NLWLKQRRLATHDFTPKSLREYVTVLRNEVEKELLAFLNAAAEDSQPFDLQELLRRFTFNIVCIV 185

  Fly   176 ALDIIAETAMGTKINAQKNPNLPYVQAVNDVTNILIKRFIHAWQRVD--------------WIF- 225
            .|.|...|.         ||:.|            :..|..|:|...              |.|
plant   186 FLGIDRCTL---------NPSSP------------VSEFDRAFQTASAVSAGRGSAPLSFVWKFK 229

  Fly   226 RLTQPTEAKRQDKAIKVMHDFTENIIRERRETLVNNSKETTPEEEVNFLGQKRRMALLDVLLQST 290
            ||......|...||:..:|:..:.|||::                      ||:.|..|.|.:..
plant   230 RLVGFGSEKELRKAVGEVHNCVDEIIRDK----------------------KRKPANQDFLSRLI 272

  Fly   291 IDGAPLSDEDIREEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVT- 354
            :.|.  |||.:|:.|.:.:..|.|||::..:...:.|:.|.|.:..|..|||.|     |..:|
plant   273 VAGE--SDETVRDMVISIIMAGRDTTSAVATRLFWLITGHEETEHDLVSEIRSV-----KEEITG 330

  Fly   355 ---LRDLGELKFMENVIKESLRLHPPVPMIGRWFAEDVEI-RGKHIPAGTNFTMGIFVLLRDPEY 415
               ...|.:|..::..:.|.:||:||||...:....|..: .|..:.||...|...:.:.|..|.
plant   331 GFDYESLKKLSLLKACLCEVMRLYPPVPWDSKHALTDDRLPDGTLVRAGDRVTYFPYGMGRMEEL 395

  Fly   416 F-ESPDEFRPERFDAD--------VPQIHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFE 471
            : |..|||:|.|:...        :.:::|:.:..|.||||.|:|::.|.::||..|:.:|..||
plant   396 WGEDWDEFKPNRWAESYDKTCCRVLKKVNPFKFPVFQAGPRVCLGEEMAYVQMKYIVASILDRFE 460

  Fly   472 LLPL 475
            :.|:
plant   461 IEPI 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_001284806.1	p450	32..495	CDD:278495	115/493 (23%)
CYP94B2	NP_566155.1	CYP86A	65..483	CDD:410687	108/450 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010