DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d2 and CYP72A13

DIOPT Version :9

Sequence 1:	NP_001284806.1	Gene:	Cyp4d2 / 31192	FlyBaseID:	FBgn0011576	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_188084.1	Gene:	CYP72A13 / 820694	AraportID:	AT3G14660	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	533	Identity:	133/533 - (24%)
Similarity:	237/533 - (44%)	Gaps:	85/533 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LGVVGVLLLVAFATLLLWDF-----LW----------RRRGNGILPGPRPLPFLGNLLMYRGLDP 51
            :.|..|.:.||...:..|.:     :|          ||:|   |.|....|.:|:|.....:..
plant     3 ISVASVTVSVAVVVVSWWVWRTLQRVWLKPKMLESYLRRQG---LAGTPYTPLVGDLKRNFSMLA 64

  Fly    52 E--------------QIMDFVKKNQRKYGRLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNL 102
            |              :|:.:..:..:.:||.:..|......:...||..|:.|.:......|.:.
plant    65 EARSKPINLTDDITPRIVPYPLQMLKTHGRTFFTWFGPIPTITIMDPEQIKEVFNKVYDFQKAHT 129

  Fly   103 YKLLNCWLGDGLLMSTGRKWHGRRKIITPTFHFKILEQFVEIFDQQSAVMV---EQLQSRADGMT 164
            :. |...:..||:...|.||...|:||.|.||.:.::..|..|.|..:.:|   ::|.:......
plant   130 FP-LGRLIAAGLVSYDGDKWTKHRRIINPAFHLEKIKNMVPAFHQSCSEIVGEWDKLVTDKQSSC 193

  Fly   165 PINIFPVICLTALDIIAETAMGTKINAQKNPNLPYVQAVNDVTNILIKRF----IHAWQRVDWIF 225
            .::|:|.:.....|:|:.||.|:  :.::...:..:||  ::..::|:.|    |..::..
plant   194 EVDIWPWLVSMTADVISRTAFGS--SYKEGQRIFELQA--ELAQLIIQAFRKAIIPGYRYF---- 250

  Fly   226 RLTQPTEAKRQDKA----IK-VMHDFTENIIRERRETLVNNSKETTPEEEVNFLGQKRRMALLDV 285
                ||:..|:.||    || ::.......:|.|.                  .|:.....||.:
plant   251 ----PTKGNRRMKAAAREIKFILRGIVNKRLRARE------------------AGEAPSDDLLGI 293

  Fly   286 LLQSTI---DGAPLSDEDIREEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGE 347
            ||:|.:   .|..:|.|::.||...|.|.|.:|||..:.:.:..:|:|.:.|.|.::|::.|.|:
plant   294 LLESNLGQTKGNGMSTEELMEECKLFYFAGQETTTVLLVWTMVLLSQHQDWQARAREEVKQVFGD 358

  Fly   348 DRKSPVTLRDLGELKFMENVIKESLRLHPPVPMIGRWFAEDVEIRGKHIPAGTNFTMGIFVLLRD 412
              |.| ....|.:||.|..::.|.|||:|||..:.|...:::::....:|.|...::.|.::.||
plant   359 --KEP-DAEGLNQLKVMTMILYEVLRLYPPVVQLTRAIHKEMQLGDLTLPGGVQISLPILLIQRD 420

  Fly   413 PEYF-ESPDEFRPERFDADVPQI--HPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLP 474
            .|.: ....||:|:||...:.:.  :..::.||:.|||.||||.||:||.|..::.:||.|. ..
plant   421 RELWGNDAGEFKPDRFKDGLSKATKNQVSFFPFAWGPRICIGQNFALLEAKMAMTLILRKFS-FE 484

  Fly   475 LGPEPRHSMNIVL 487
            |.|...|:...||
plant   485 LSPSYVHAPYTVL 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_001284806.1	p450	32..495	CDD:278495	123/488 (25%)
CYP72A13	NP_188084.1	p450	24..512	CDD:299894	128/512 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.860