DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d2 and CYP72A8

DIOPT Version :9

Sequence 1:	NP_001284806.1	Gene:	Cyp4d2 / 31192	FlyBaseID:	FBgn0011576	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_188080.1	Gene:	CYP72A8 / 820690	AraportID:	AT3G14620	Length:	515	Species:	Arabidopsis thaliana

Alignment Length:	539	Identity:	127/539 - (23%)
Similarity:	232/539 - (43%)	Gaps:	100/539 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LGVVGVLLLVAFATLLLWDFL---W----------RRRGNGILPGPRPLPFL-GNLLMYRGLDPE 52
            :.|...:::|...|:.:|..|   |          :|:|   |.| .|..|| |::.....:..:
plant     9 VAVAAAVVVVTTVTVWIWKGLNVAWLRPKKNEAYLKRQG---LSG-TPFTFLVGDIKREASMVEQ 69

  Fly    53 Q--------------IMDFVKKNQRKYGRLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLY 103
            :              :|..:::..:.:|:...:|:....:|..|.|..|:.||:......|..::
plant    70 EKSRPINLTDDYTHRVMPLIQQTVKDHGKTSYMWMGPIASVIVTKPEHIKDVLNRVYDFPKPPVH 134

  Fly   104 KLLNCWLGDGLLMSTGRKWHGRRKIITPTFHFKILEQFVEIFDQQSAVMV---EQLQSRADGMTP 165
            .::..: ..|:.:..|.||...||||.|:||.:.|:..:..|.:..:.|:   |:|.:.......
plant   135 PIVELF-ATGVALYEGEKWSKHRKIINPSFHLEKLKIMIPAFYESCSEMISKWEKLVTEQGSSNE 198

  Fly   166 INIFPVICLTALDIIAETAMGTKINAQKNPNLPYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQP 230
            |:::|.:.....|:|:.||.|:.....|.                             ||.| |.
plant   199 IDVWPYLGDLTSDVISRTAFGSSYEEGKR-----------------------------IFEL-QE 233

  Fly   231 TEAKRQDKAIKV----------------MHDFTENIIRERRETLVNNSK--ETTPEEEVNFLGQK 277
            .:.:|..||:::                |....:.:....||.::...:  :|         |:.
plant   234 EQGRRVLKALELAFIPGMRFLPTKNNLRMRQINKEVKSRLREIIMKRQRGMDT---------GEA 289

  Fly   278 RRMALLDVLLQSTIDGAPLSDEDIREEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIR 342
            .:..||.:||:|......:|.||:.||...|.|.|.:||...:.:.:..:|.|.:.|.:.::||.
plant   290 PKNDLLGILLESNSGDHGMSIEDVVEECRLFHFAGQETTAVLLVWTMIMLSHHQKWQDQAREEIL 354

  Fly   343 DVLGEDRKSPVTLRDLGELKFMENVIKESLRLHPPVPMIGRWFAEDVEI-RGKHIPAGTNFTMGI 406
            .|:|::.|.  ....|..||.|..::.|.|||:||..::||...::.:: ....:|.|....:.:
plant   355 KVIGKNNKP--NFDALSRLKTMSMILNEVLRLYPPGILLGRTVEKETKLGEDMTLPGGAQVVIPV 417

  Fly   407 FVLLRDPEYF-ESPDEFRPERFDADVPQI--HPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLR 468
            .::.||||.: |...||.||||...:.:.  :..:::||..|||.|.||.||::|.|..:..:|:
plant   418 LMVHRDPELWGEDVHEFNPERFADGISKATKNQVSFLPFGWGPRFCPGQNFALMEAKMALVLILQ 482

  Fly   469 HFELLPLGPEPRHSMNIVL 487
            .|. ..|.|...|:.:.||
plant   483 RFS-FELSPSYTHAPHTVL 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_001284806.1	p450	32..495	CDD:278495	118/496 (24%)
CYP72A8	NP_188080.1	p450	26..515	CDD:299894	124/522 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.860