DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d2 and CYP704A2

DIOPT Version :9

Sequence 1:	NP_001284806.1	Gene:	Cyp4d2 / 31192	FlyBaseID:	FBgn0011576	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_182075.1	Gene:	CYP704A2 / 819159	AraportID:	AT2G45510	Length:	511	Species:	Arabidopsis thaliana

Alignment Length:	462	Identity:	120/462 - (25%)
Similarity:	212/462 - (45%)	Gaps:	54/462 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 YRVWILHQLAVFSTDPRDIEFVLS------SQQHITKNNLYKLLNCWLGDGLLMSTGRKWHGRRK 127
            ||.....|..:.:.|||::|.:|.      |:.|.::.|:..|    ||.|:....|.||..:||
plant    71 YRFLSPGQSEILTADPRNVEHILKTRFDNYSKGHSSRENMADL----LGHGIFAVDGEKWRQQRK 131

  Fly   128 IITPTFHFKILEQF-VEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIAETAMGTK--- 188
            :.:..|..::|..| ..:|.:.::.:|..:...|......:...::....||.|.:...|.:
plant   132 LSSFEFSTRVLRDFSCSVFRRNASKLVGFVSEFALSGKAFDAQDLLMRCTLDSIFKVGFGVELKC 196

  Fly   189 INAQKNPNLPYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQPTEAKRQDKAIKVMHDFTENIIRE 253
            ::........:::|.::.......|||....::.|.|.:...::.|   |:|..:..|..::|..
plant   197 LDGFSKEGQEFMEAFDEGNVATSSRFIDPLWKLKWFFNIGSQSKLK---KSIATIDKFVYSLITT 258

  Fly   254 RRETLVNNSKETTPEEEVNFLGQKRRMALLDVLLQSTIDGAPLSDEDIREEVDTFMFEGHDTTTS 318
            :|:.|. ..:.|...|::          |...|::|..|...::|:.:|:.:..||..|.|||.:
plant   259 KRKELA-KEQNTVVREDI----------LSRFLVESEKDPENMNDKYLRDIILNFMIAGKDTTAA 312

  Fly   319 AISFCLYEISRHPEVQQRLQQEIRDVLGEDRKS--------PVTLRDLGELKFMENVIKESLRLH 375
            .:|:.||.:.::|.||:::.||||||.....|:        .:....|.|:.::...:.|:|||:
plant   313 LLSWFLYMLCKNPLVQEKIVQEIRDVTFSHEKTTDVNGFVESINEEALDEMHYLHAALSETLRLY 377

  Fly   376 PPVPMIGRWFA-EDVEIRGKHIPAGTN-----FTMGIFVLLRDPEYFESPDEFRPERFDAD---V 431
            ||||:..|... :||...|..:..|.|     :.||....:    :.:..:||:|||:..|   .
plant   378 PPVPVDMRCAENDDVLPDGHRVSKGDNIYYIAYAMGRMTYI----WGQDAEEFKPERWLKDGLFQ 438

  Fly   432 PQIHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLPLGPEPR---HSMNIVLRSANGV 493
            |: .|:.:|.|.||||.|:|:.||..:|| .||..|.||....:..|..   :...:.|....|:
plant   439 PE-SPFKFISFHAGPRICLGKDFAYRQMK-IVSMALLHFFRFKMADENSKVYYKRMLTLHVDGGL 501

  Fly   494 HLGLKPR 500
            ||...||
plant   502 HLCAIPR 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_001284806.1	p450	32..495	CDD:278495	116/455 (25%)
CYP704A2	NP_182075.1	PLN03195	15..509	CDD:215627	120/462 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H82150
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.920