DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d2 and CYP704A1

DIOPT Version :9

Sequence 1:	NP_001284806.1	Gene:	Cyp4d2 / 31192	FlyBaseID:	FBgn0011576	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_850427.2	Gene:	CYP704A1 / 819098	AraportID:	AT2G44890	Length:	511	Species:	Arabidopsis thaliana

Alignment Length:	457	Identity:	118/457 - (25%)
Similarity:	210/457 - (45%)	Gaps:	58/457 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 QLAVFSTDPRDIEFVLSSQQH------ITKNNLYKLLNCWLGDGLLMSTGRKWHGRRKIITPTFH 134
            |..:|:.|||::|.:|.::.|      :...||..|    ||.|:....|.||..:||:::..|.
plant    78 QSEIFTADPRNVEHILKTRFHNYSKGPVGTVNLADL----LGHGIFAVDGEKWKQQRKLVSFEFS 138

  Fly   135 FKILEQF-VEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIAETAMGTK---INAQKNP 195
            .::|..| ..:|...::.:|..:...|......:...::....||.|.:...|.:   ::.....
plant   139 TRVLRNFSYSVFRTSASKLVGFIAEFALSGKSFDFQDMLMKCTLDSIFKVGFGVELGCLDGFSKE 203

  Fly   196 NLPYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQPTEAKRQDKAIKVMHDFTENIIRERRETLVN 260
            ...:::|.::.......|....:.::.....:...:..|   |:|.::..|..::|..:|:.|
plant   204 GEEFMKAFDEGNGATSSRVTDPFWKLKCFLNIGSESRLK---KSIAIIDKFVYSLITTKRKEL-- 263

  Fly   261 NSKE--TTPEEEVNFLGQKRRMALLDVLLQSTIDGAPLSDEDIREEVDTFMFEGHDTTTSAISFC 323
             |||  |:..|::          |...||:|..|...::|:.:|:.:...|..|.|||.:::|:.
plant   264 -SKEQNTSVREDI----------LSKFLLESEKDPENMNDKYLRDIILNVMVAGKDTTAASLSWF 317

  Fly   324 LYEISRHPEVQQRLQQEIRDVLGEDRKS--------PVTLRDLGELKFMENVIKESLRLHPPVPM 380
            ||.:.::|.||:::.||||||.....|:        .||...|.:::::...:.|::||:||||.
plant   318 LYMLCKNPLVQEKIVQEIRDVTSSHEKTTDVNGFIESVTEEALAQMQYLHAALSETMRLYPPVPE 382

  Fly   381 IGRWFA-EDVEIRGKHIPAGTN-----FTMGIFVLLRDPEYFESPDEFRPERFDAD---VPQIHP 436
            ..|... :||...|..:..|.|     :.||....:    :.:..:||:|||:..|   .|: ..
plant   383 HMRCAENDDVLPDGHRVSKGDNIYYISYAMGRMTYI----WGQDAEEFKPERWLKDGVFQPE-SQ 442

  Fly   437 YAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLPLGPE---PRHSMNIVLRSANGVHLGLK 498
            :.:|.|.||||.|||:.||..:|| .||..|.||....:..|   ..:...:.|....|:||...
plant   443 FKFISFHAGPRICIGKDFAYRQMK-IVSMALLHFFRFKMADENSKVSYKKMLTLHVDGGLHLCAI 506

  Fly   499 PR 500
            ||
plant   507 PR 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_001284806.1	p450	32..495	CDD:278495	114/450 (25%)
CYP704A1	NP_850427.2	CYP86A	69..501	CDD:410687	113/448 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H82150
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.920