Protein Alignment Cyp4d2 and Cyp4x1

DIOPT Version :9

• Sequence 1: NP_001284806.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001003947.1
• Gene: Cyp4x1 / 81906
• MGIID: 1932403
• Length: 507
• Species: Mus musculus
• Alignment Length: 509
• Identity: 173/509 - (33%)
• Similarity: 263/509 - (51%)
• Gaps: 34/509 - (6%)

  Fly     2 LGVVGVLLLVAFATLLLWDFLWRRRGNGIL------PGPRPLPFLGNLLMYRGLDPEQIMDFVKK 60
            |.:|..|.||....:.|  :|.|:|   :|      |||.....||:....:..:.|.:.:.||
Mouse    16 LALVFCLALVLMQAMKL--YLRRQR---LLRDLSPFPGPPAHWLLGHQKFLQEDNMETLDEIVK- 74

  Fly    61 NQRKYGRLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLYKLLNCWLGDGLLMSTGRKWHGR 125
               |:...:..|:....|.|.....|...:..|:.......|::||...:|.|||...|.:|...
Mouse    75 ---KHPCAFPCWVGPFQAFFYIYDPDYAKIFLSRTDPKMQYLHQLLTPCIGRGLLNLDGPRWFQH 136

  Fly   126 RKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSR-ADGMTPINIFPVICLTALDIIAETAMGTKI 189
            |.::||.||..||:..|:.......||:::.:.. ....|.|.:|..|.|..||||.:.|.|.:.
Mouse   137 RCLLTPAFHQDILKPCVDTMAHSVKVMLDKWEKMWTTQETTIEVFEHINLMTLDIIMKCAFGQET 201

  Fly   190 NAQKNPNL-PYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQPTEAKRQDKAIKVMHDFTENIIRE 253
            |.|.|... .||:|..::..|:..|..:.|...|.||:|: |.....|:.. ||:|.:||.||::
Mouse   202 NCQINGTYESYVKATFELGEIISSRLYNFWHHHDIIFKLS-PKGHCFQELG-KVIHQYTEKIIQD 264

  Fly   254 RRETLVNNSKETTPEEEVNFLGQKRRMALLDVLLQSTI-DGAPLSDEDIREEVDTFMFEGHDTTT 317
            |::.|.|..|:...:....|         ||::|.:.. |....||.|:|.||:|||:.|||.:.
Mouse   265 RKKILKNQVKQDDTQTSQIF---------LDIVLSAQAEDERAFSDADLRAEVNTFMWAGHDASA 320

  Fly   318 SAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESLRLHPPVPMIG 382
            ::||:.||.::.:||.|.|.:.|||.:||:.  |.:|...|.|:.:....|||:|||.||||.|.
Mouse   321 ASISWLLYCLALNPEHQDRCRTEIRSILGDG--SSITWEQLDEMSYTTMCIKETLRLIPPVPSIS 383

  Fly   383 RWFAEDVEIRGKH-IPAGTNFTMGIFVLLRDPEYFESPDEFRPERFDAD-VPQIHPYAYIPFSAG 445
            |..::.:.:...| :|||....:.|:.|..:|..:..|..|.|.||..: ..|.||.|::|||:|
Mouse   384 RELSKPLTLPDGHSLPAGMTVVLSIWGLHHNPAVWNDPKVFDPLRFTKENSDQRHPCAFLPFSSG 448

  Fly   446 PRNCIGQKFAMLEMKSTVSKLLRHFELLP-LGPEPRHSMNIVLRSANGVHLGLK 498
            |||||||:|||||:|..::.:|.||::.| |...|..|.:.|||..:|::|.||
Mouse   449 PRNCIGQQFAMLELKVAIALILLHFQVAPDLTRPPAFSSHTVLRPKHGIYLHLK 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_001284806.1	p450	32..495	CDD:278495	160/468 (34%)
Cyp4x1	NP_001003947.1	p450	47..499	CDD:278495	160/468 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845091
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.750