Protein Alignment Cyp4d2 and cyp26b1

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001072655.1
• Gene: cyp26b1 / 780112
• XenbaseID: XB-GENE-991500
• Length: 511
• Species: Xenopus tropicalis
• Alignment Length: 504
• Identity: 119/504 - (23%)
• Similarity: 211/504 - (41%)
• Gaps: 92/504 - (18%)

  Fly     4 VVGVLLLVAFATLLLWDFLW--RRRGNGILPGPR---PLPFLGNLL--MYRGLDPEQIMDFVKKN 61
            :|.|.||:| .:..||...|  .|..:..||.|:   ..|.:|...  :.:|      .||....
 Frog    19 LVSVALLLA-VSQQLWQLRWAATRDKSCKLPIPKGSMGFPLVGETFHWILQG------SDFQSSR 76

  Fly    62 QRKYGRLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLYKLLNCWLG-DGLLMSTGRKWHGR 125
            :.|||.:::..:|.:..:..|...::..:|..:.|:......:.....|| :.|..|.|.....:
 Frog    77 REKYGNVFKTHLLGRPLIRVTGAENVRKILMGEHHLVSTEWPRSTRMLLGPNSLANSIGDIHRHK 141

  Fly   126 RKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIAETAMGTKIN 190
            ||:.:..|..:.||.::   .:...|:.:.|:..:.....||::   |                .
 Frog   142 RKVFSKIFSHEALESYL---PKIQLVIQDTLRVWSSNPESINVY---C----------------E 184

  Fly   191 AQKNPNLPYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQPTEAKRQDKAIKVMHDFTENIIR--- 252
            |||   |.:..|:                ||...|||:.    :...:..:|...|.||:..
 Frog   185 AQK---LTFRMAI----------------RVLLGFRLSD----EELSQLFQVFQQFVENVFSLPV 226

  Fly   253 -----------ERRETLVNNSKETTPEEEVNFLGQKRRMALLDVLLQSTID-GAPLSDEDIREEV 305
                       ..||.|:.:.::...|:..|..|:....| ||:|::|..: |..|:.:::::..
 Frog   227 DVPFSGYRRGIRAREMLLKSLEKAIQEKLQNTQGKDYADA-LDILIESGKEHGKELTMQELKDGT 290

  Fly   306 DTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIR--DVL--GEDRKSPVTLRDLGELKFMEN 366
            ...:|..:.||.||.:..:.::.:||.|.::|::|:|  .:|  |...:..:.:..:..|.:::.
 Frog   291 LELIFAAYATTASASTSLIMQLLKHPSVLEKLREELRGNSILHNGCVCEGALRVETISSLHYLDC 355

  Fly   367 VIKESLRLHPPVPMIGRWFAEDVEIRGKHIPAGTNFTMGIFVLLRDPE----YFESPDEFRPERF 427
            ||||.|||..||....|...:..|:.|..||.|    ..:...:||..    .|:..|.|.|:||
 Frog   356 VIKEILRLFSPVSGGYRTVLQTFELDGFQIPKG----WSVLYSIRDTHDTAPVFKDVDVFDPDRF 416

  Fly   428 DADVPQIHP--YAYIPFSAGPRNCIGQKFAMLEMKSTVSKL--LRHFEL 472
            ..|..:...  :.|:||..|.|||:|:..|.|.:|....:|  :..|||
 Frog   417 GQDRTEDKDGRFHYLPFGGGVRNCLGKHLAKLFLKVLAIELASMSRFEL 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	100/435 (23%)
cyp26b1	NP_001072655.1	CYP26B1	60..489	CDD:410730	106/462 (23%)