Protein Alignment Cyp4d2 and cyp46a1.3

DIOPT Version :9

• Sequence 1: NP_001284806.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001027517.1
• Gene: cyp46a1.3 / 613109
• XenbaseID: XB-GENE-969052
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 553
• Identity: 147/553 - (26%)
• Similarity: 266/553 - (48%)
• Gaps: 115/553 - (20%)

  Fly     5 VGVLLLVAFATLLL---------------------WDFLWRRRGNGILPG-PRPLPFLG------ 41
            :|:..|:.:|.|||                     :|.         :|| ||...|||
 Frog     1 MGLWALIGWAALLLLALILICFLLFSGYIHYIHMKYDH---------IPGPPRDSFFLGHSPTML 56

  Fly    42 -----NLLMYRGLDPEQIMDFVKKNQRKYGRLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNN 101
                 |||||     :..:.:|    :|||.:.|:..||::.:....|..::.:|.|.:: :|:.
 Frog    57 RLMKNNLLMY-----DHFLGWV----QKYGPVVRINGLHRVIILVVSPEAVKELLMSPKY-SKDK 111

  Fly   102 LYKLL-NC----WLGDGLLMSTGR---KWHGRRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQS 158
            .|.:: |.    ::|.||:  |.|   .||.:|:|:.|.|....|...:..|::::..::|:|..
 Frog   112 FYDVIANMFGVRFMGKGLV--TDRDYDHWHKQRRIMDPAFSRTYLMGLMGPFNEKAEELMEKLME 174

  Fly   159 RADGMTPINIFPVICLTALDIIAETAMGTKINAQKNPNLPYVQAVN-------DVTNILIKRFIH 216
            :|||...|.:..::....||:|.:.|.|.::|:..:...|:.:|::       ::.|.:::
 Frog   175 KADGKCEIKMHDMLSRLTLDVIGKVAFGMELNSLNDDLTPFPKAISLVMKGIVEMRNPMVR---- 235

  Fly   217 AWQRVDWIFRLTQPTEAKRQDKAIKVMHDFTENIIRERRETLVNNSKETTPEEEVNFLGQKRRMA 281
                    :.|.:....::..::|:::....:..| |||:..:.:.:|..
 Frog   236 --------YSLAKRGFIRKVQESIRLLRQTGKECI-ERRQKQIQDGEEIP--------------- 276

  Fly   282 LLDVLLQSTIDGAPLSD----EDIREEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIR 342
             :|:|.| .:.||.:.:    |.:.:...||...|.:||.:.:||.:.|:.|:||:.::.|.||.
 Frog   277 -VDILTQ-ILKGAAMEEECDPEILLDNFVTFFIAGQETTANQLSFVVMELGRNPEILEKAQAEID 339

  Fly   343 DVLGEDRKSPVTLRDLGELKFMENVIKESLRLHPPVPMIGRWFAEDVEIRGKHIPAGTNFTMGIF 407
            :|:|.  |..:...|||:|:::..|:||:|||:|..|...|...||:.|.|..:|......:..:
 Frog   340 EVIGS--KRDIEYEDLGKLQYLSQVLKETLRLYPTAPGTSRGLTEDMVIDGVKVPENVTIMLNSY 402

  Fly   408 VLLRDPEYFESPDEFRPERFDADVPQIHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFEL 472
            ::.|..:|:..|..|.|:||..|.|:.: |:|.|||.|||:||||.|:.:|.|..::|||:.:|.
 Frog   403 IMGRMEQYYSDPLTFNPDRFSPDAPKPY-YSYFPFSLGPRSCIGQVFSQMEAKVVMAKLLQRYEF 466

  Fly   473 -LPLGPEPRHSMNIV----LRSANGVHLGLKPR 500
             |..|    .|..|:    ||..:||...|:||
 Frog   467 ELAEG----QSFKILDTGTLRPLDGVICRLRPR 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_001284806.1	p450	32..495	CDD:278495	137/498 (28%)
cyp46a1.3	NP_001027517.1	p450	40..491	CDD:306555	137/499 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910