Protein Alignment Cyp4d2 and cyp19a1b

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: XP_021326198.1
• Gene: cyp19a1b / 60640
• ZFINID: ZDB-GENE-001103-4
• Length: 513
• Species: Danio rerio
• Alignment Length: 527
• Identity: 135/527 - (25%)
• Similarity: 229/527 - (43%)
• Gaps: 91/527 - (17%)

  Fly     4 VVGVLLLVAFATLLLWDFLWRR-------RGNGILPGPRPLPFLGNLLMYRGLDPEQIMDFVKKN 61
            |.|.|||:. .||:|  .|..|       |....||||.....||.:|.|.......|.......
Zfish    16 VQGTLLLLT-GTLML--ILLHRIFGVKNWRNQSALPGPGWWLGLGPVLSYSRFLWMGIGTACNYY 77

  Fly    62 QRKYGRLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLY-------KLLNCWLG---DGLLM 116
            ..|||.:.||||..:..|..:     :.|.|:..|:.|:|.|       |.|.| :|   .|::.
Zfish    78 NEKYGSIARVWINGEETVILS-----KQVSSAVYHVLKSNNYTGRFASAKGLQC-IGMFEQGIIF 136

  Fly   117 STG-RKWHGRRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDII 180
            ::. .||...|...|.......|::.||:....:...::.||...|....:::..::....:|:.
Zfish   137 NSNIAKWKKVRTYFTKALTGPGLQKSVEVCVSATNRQLDVLQEFTDASGHVDVLNLLRCIVVDVS 201

  Fly   181 AETAMGTKINAQKNPNLPYVQAVNDVTNILIK--RFIHAWQ----------RVDWIFRLTQPTEA 233
            ....:...:|.::               :|||  |:...||          ::|:::|
Zfish   202 NRLFLRIPLNEKE---------------LLIKIHRYFSTWQTVLIQPDIFFKLDFVYR------- 244

  Fly   234 KRQDKAIKVMHDFTENIIRERRETLVNNSKETTPEEEVNFLGQKRRMALLDVLLQSTIDGAPLSD 298
             :...|.|.:.|....::.::|:. :||:::.   :|::|        ..:::.....|  .||.
Zfish   245 -KYHLAAKELQDEMGKLVEQKRQA-INNTEKL---DEMDF--------ATELIFAQNHD--ELSV 294

  Fly   299 EDIREEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKF 363
            :|:|:.|...:....||.:.::.|.|..:.::..|::::.|||:..:|   ...|...||.:|..
Zfish   295 DDVRQCVLEMVIAAPDTLSISLFFMLLLLKQNSAVEEQIVQEIQSQIG---SRDVESADLQKLNV 356

  Fly   364 MENVIKESLRLHPPVPMIGRWFAEDVEIRGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERFD 428
            :|..||||||.||.|..|.|...||..|.|..:..|||..:.| ..:...|:|:.|:||..|.|:
Zfish   357 LERFIKESLRYHPVVDFIMRQSLEDDYIDGYRVAKGTNLILNI-GRMHKTEFFKKPNEFSLENFE 420

  Fly   429 ADVPQIHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLPLGPEPRHSMNI-VLRSANG 492
            ..||..:   :.||..|||.|:|:..||:..|:.:..:|..|.:.     |||...| .:|..|
Zfish   421 NTVPSRY---FQPFGCGPRACVGKHIAMVMTKAILVTMLSRFTVC-----PRHGCTISTIRQTN- 476

  Fly   493 VHLGLKP 499
             :|.::|
Zfish   477 -NLSMQP 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	111/452 (25%)
cyp19a1b	XP_021326198.1	CYP19A1	72..486	CDD:410709	115/468 (25%)