Protein Alignment Cyp4d2 and cyp3c4

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001071016.1
• Gene: cyp3c4 / 558541
• ZFINID: ZDB-GENE-060929-96
• Length: 507
• Species: Danio rerio
• Alignment Length: 537
• Identity: 150/537 - (27%)
• Similarity: 251/537 - (46%)
• Gaps: 91/537 - (16%)

  Fly     9 LLVAFATLLLWDFLWRRR-----GNGILPGPRPLPFLGNLLMY-RGLDPEQIMDFVKKNQRKYGR 67
            |:|...|||....:|..|     |   :|||||.||:|.||.| :||     .:|..:..:|||:
Zfish    13 LVVLVITLLFIYGVWPHRFFIKLG---IPGPRPWPFVGTLLSYAKGL-----CNFDMECAKKYGK 69

  Fly    68 LYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLYKLLNCWLG---DGLLMSTGRKWHGRRKII 129
            ::.::......:...|...|:.||..:.:....|..|......|   ||::|....:|...|..:
Zfish    70 VWGIYDGRLPILMVADLEVIKVVLVKECYSNFINRRKRTTGLAGPFSDGIIMVKDERWKRMRSTL 134

  Fly   130 TPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIAETAMGTKINAQKN 194
            :|.|....|::...|....:...::.:|.: |...|:.|..|:...:||:|..::....|::..|
Zfish   135 SPYFTSGRLKEIFPIAMTHADRFIKNMQKK-DPEQPVKIKEVVAPYSLDVITSSSFSVDIDSINN 198

  Fly   195 PNLPYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQP------------TEAKRQDKAI--KVMHD 245
            |..|:|        |.:|:||.        |.:..|            ...|:....:  |...|
Zfish   199 PEDPFV--------INVKKFIQ--------FNMFNPLLLLILLFPSLAIPLKKMGVTLFSKSAMD 247

  Fly   246 FTENIIRERRETLVNNSKETTPEEEVNFLGQKRRMALLDVLLQSTIDGAPLSDEDIREE-----V 305
            |..:::::.::   :::||:  |..|:|         |.::||:.|....:.|.|..|:     .
Zfish   248 FFYSVLKKIKD---DHNKES--EGRVDF---------LKLMLQNQIPDDQIQDSDTSEQPAKGLT 298

  Fly   306 D--------TFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELK 362
            |        .|:..|::||::.::|.||.::.:|:..::|.:||......|  :|:|...|..:.
Zfish   299 DHEILSQSLVFILGGYETTSTTLTFLLYNLATNPDCLEKLVEEIDKNFPLD--TPITYDALMRMD 361

  Fly   363 FMENVIKESLRLHPPVPMIGRWFAEDVEIRGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERF 427
            ::|..|.||:||.|..|.:.|...:.|.|.|..||.||...:..:||..||:.:|||.|||||||
Zfish   362 YLEMAINESMRLLPTAPRLERSAKKTVVINGLTIPEGTLVGIPTYVLSHDPDIWESPGEFRPERF 426

  Fly   428 DAD-VPQIHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFEL-------LPLGPEPRHSMN 484
            ..: ..:...||:|||..|||||||.::|::.||..|.|||::|.:       :||      .||
Zfish   427 SPENKSEFLQYAFIPFGLGPRNCIGMRYAVMIMKLFVVKLLQNFSVETCKETQIPL------EMN 485

  Fly   485 IVLRSANGVHLGLKPRA 501
            :..:....:.|.|.||:
Zfish   486 VTFQPKVPITLKLIPRS 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	122/466 (26%)
cyp3c4	NP_001071016.1	cytochrome_P450	66..497	CDD:477761	124/469 (26%)