Protein Alignment Cyp4d2 and cyp4b1.2

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001017348.1
• Gene: cyp4b1.2 / 550102
• XenbaseID: XB-GENE-963387
• Length: 515
• Species: Xenopus tropicalis
• Alignment Length: 509
• Identity: 178/509 - (34%)
• Similarity: 279/509 - (54%)
• Gaps: 41/509 - (8%)

  Fly     5 VGVLLLVAFATLLLWDFLW---RRRGNGILPGPRPLP---FLGNLLMYR--GLDPEQIMDFVKKN 61
            |.:|||.|:|       |:   ||....::|.|.| |   ..|::..:|  |.|.:::|.:|
 Frog    30 VVLLLLKAYA-------LYSRGRRFAAALVPFPGP-PAHWLYGHVNQFRRDGKDLDRLMVWV--- 83

  Fly    62 QRKYGRLYRVWI---LHQLAVFSTDPRDIEFVLSSQQHITKNNLYKLLNCWLGDGLLMSTGRKWH 123
             .||...:.:||   ...|.:  |||...:.|.......|... |..|..|:|.|||:.:|..|.
 Frog    84 -NKYPNAFPLWIGKFFGTLII--TDPDYAKVVFGRSDPKTSTG-YNFLVPWIGKGLLILSGNTWF 144

  Fly   124 GRRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIAETAMGTK 188
            ..|::|||.||:.:|:.:|.:....:.:|:::|...::....:.:|..:.|..||.|.:.|....
 Frog   145 QHRRLITPGFHYDVLKPYVSLISDSTKIMLDELDVYSNKDESVELFQHVSLMTLDSIMKCAFSYH 209

  Fly   189 INAQKNPNLPYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQPTEAKRQDKAIKVMHDFTENIIRE 253
            .|.|.:.:..|:|||.|::.:..:|........:.|:.|:  ....|..||.:::|..|:.:|.:
 Frog   210 SNCQTDKDNDYIQAVYDLSWLTQQRIRTFPYHSNLIYFLS--PHGFRFRKACRIVHLHTDKVIGQ 272

  Fly   254 RRETLVNNSKETTPEEEVNFLGQKRRMALLDVLLQSTID-GAPLSDEDIREEVDTFMFEGHDTTT 317
            |::.|.:       :||:..:.:||.:..||:||.|..: |..||.||:|.|||||||||||||:
 Frog   273 RKKLLES-------KEELEKVQKKRHLDFLDILLCSKDENGQGLSHEDLRAEVDTFMFEGHDTTS 330

  Fly   318 SAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESLRLHPPVPMIG 382
            |.||:.||.::.|||.||:.::||.:.|||  :..:...||..:.:....|||||||:||||.:.
 Frog   331 SGISWILYCMATHPEHQQKCREEISEALGE--RQTMEWDDLNRMPYTTMCIKESLRLYPPVPSVS 393

  Fly   383 RWFAEDVEIR-GKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERFDAD-VPQIHPYAYIPFSAG 445
            |..|:.:... |:.:|||...::.|:.:.|:|..::.|:.|.|.||..: ..:.|.:|::||:||
 Frog   394 RELAKPITFHDGRSLPAGMLVSLQIYAIHRNPNVWKDPEIFDPLRFSPENSSKRHSHAFVPFAAG 458

  Fly   446 PRNCIGQKFAMLEMKSTVSKLLRHFELLP-LGPEPRHSMNIVLRSANGVHLGLK 498
            |||||||.|||.|||..|:..|:.|||.| |...|.....:||||.||:|:.||
 Frog   459 PRNCIGQNFAMNEMKVAVALTLKRFELSPDLSKPPLKQPQLVLRSKNGIHVYLK 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	154/435 (35%)
cyp4b1.2	NP_001017348.1	CYP4B-like	76..510	CDD:410771	159/451 (35%)