Protein Alignment Cyp4d2 and cyp51a1

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001016194.1
• Gene: cyp51a1 / 548948
• XenbaseID: XB-GENE-985396
• Length: 499
• Species: Xenopus tropicalis
• Alignment Length: 515
• Identity: 125/515 - (24%)
• Similarity: 226/515 - (43%)
• Gaps: 71/515 - (13%)

  Fly     8 LLLVAFATLLLWDFLWRRRGNGILPGP---RPLPFLGNLLMYRGLDPEQIMDFVKKNQRKYGRLY 69
            ||.:|:.:.|.:..|.......:...|   ..:||||:.:.: |..|   :.|::....|||.::
 Frog    32 LLALAYVSKLAFKHLQAEDPGNVKYPPFISSNIPFLGHAIAF-GKSP---ISFLENAYDKYGPVF 92

  Fly    70 RVWILHQLAVF--STDPRDIEFVLSSQQHITKNNLY-KLLNCWLGDGLLMSTGRKWHGRRKIITP 131
            ...::.:...:  .:|...:.| .|..:.:...::| :|.....|.|:...........:|.:..
 Frog    93 SFTMVGKTFTYLVGSDAAALLF-NSKNEDLNAEDVYSRLTTPVFGKGVAYDVPNPIFLEQKKMLK 156

  Fly   132 T----FHFKILEQFVEIFDQQSAVMVEQLQSRAD--GMTPI-NIF----PVICLTALDIIAETAM 185
            |    .|||...|.:|          |:.|...:  |.:.: |:|    .:|.|||    :....
 Frog   157 TGLNIAHFKTHVQMIE----------EETQEYFERWGDSGVRNLFEALSELIILTA----SRCLH 207

  Fly   186 GTKINAQKNPNLPYVQAVNDVTNILIKRFIH-AWQRVDWIFRLTQPTEAKRQDKAIKVMHDFTEN 249
            |.:|.:..|..:..:.|..|      ..|.| ||....|   |..|: .:|:|:|.:.:.:....
 Frog   208 GKEIRSMLNERVAQLYADLD------GGFTHAAWLLPGW---LPLPS-FRRRDRAHREIKNIFYQ 262

  Fly   250 IIRERRETLVNNSKETTPEEEVNFLGQKRRMALLDVLLQSTI-DGAPLSDEDIREEVDTFMFEGH 313
            :|::||     ||.|             |...:|..||.:|. ||.||:|::|...:...:..|.
 Frog   263 VIQKRR-----NSAE-------------REDDMLQTLLDATYKDGTPLNDDEIAGMLIGLLLAGQ 309

  Fly   314 DTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESLRLHPPV 378
            .|:::..::..:.::::..:|.:...|.:.|.||| ..|:....|.:|:.::..|||:|||.||:
 Frog   310 HTSSTTSAWMGFFLAKNKSLQAQCFAEQKAVCGED-LPPLNYDQLKDLQALDRCIKETLRLRPPI 373

  Fly   379 PMIGRWFAEDVEIRGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERFDADVPQI-HPYAYIPF 442
            ..:.|.......:.|.:||.|....:...|..|..:.::...:|.|:|:..|.|.. ..:||:||
 Frog   374 MTMMRMARTPQSVAGYNIPPGHQVCVSPTVNHRLRDTWDKNTDFNPDRYLHDNPAAGEKFAYVPF 438

  Fly   443 SAGPRNCIGQKFAMLEMKSTVSKLLR--HFELLPLGPEPRHSMNIVLRSANGVHLGLKPR 500
            .||...|||:.||.:::|:..|.:||  .|||:. |..|..:...::.:.|...:..|.|
 Frog   439 GAGRHRCIGENFAYVQIKTIWSTMLRMYEFELVD-GYFPTINYTTMIHTPNNPVIRYKRR 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	108/447 (24%)
cyp51a1	NP_001016194.1	CYP51-like	84..495	CDD:410668	110/455 (24%)