Protein Alignment Cyp4d2 and Cyp3a41a

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_059092.2
• Gene: Cyp3a41a / 53973
• MGIID: 1858451
• Length: 504
• Species: Mus musculus
• Alignment Length: 513
• Identity: 143/513 - (27%)
• Similarity: 254/513 - (49%)
• Gaps: 104/513 - (20%)

  Fly     9 LLVAFATLLLWDF------LWRRRGNGILPGPRPLPFLGNLL-MYRGLDPEQIMDFVKKNQRKYG 66
            :|:|...:||:.:      |::::|   :|||:||||||.:| .|:||     ..|..:...|||
Mouse    13 VLLAIILVLLYRYGTRTHGLFKKQG---IPGPKPLPFLGTVLNYYKGL-----WKFDMECYEKYG 69

  Fly    67 RLYRVWILH--QLAVF-STDPRDIEFVLSSQQHITKNNLYKLLNCW--------------LGDGL 114
               :.|.|.  |:.:| .|||..|           ||.|.|  .|:              :...:
Mouse    70 ---KTWGLFDGQMPLFVITDPEMI-----------KNVLVK--ECFSVFTNRREFGPVGIMSKAI 118

  Fly   115 LMSTGRKWHGRRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDI 179
            .:|...:|...|.:::|||....|::...:.:|...::|:.|...|:...|:.:..|:...::|:
Mouse   119 SISKDEEWKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLMQEAEKGKPVTMKDVLGAYSIDV 183

  Fly   180 IAETAMGTKINAQKNPNLPYVQAVNDVTNILIKRFIHAWQRVDW----IFRLTQPTEAKRQDKAI 240
            |..|:.|..:::..||..|:|:....:.            |||:    :|.:
Mouse   184 ITSTSFGVNVDSLNNPEDPFVEKAKGIL------------RVDFFDPLVFSV------------- 223

  Fly   241 KVMHDFTE------NIIRERRETL------VNNSKETTPEEEVNFLGQKRRMALLDVLLQSTIDG 293
             |:..|..      ||....::::      ||..||:..:.:     ||.|:..|.:::.:..:.
Mouse   224 -VLFPFLTPVYEMLNICMFPKDSIEFFKKFVNRMKESRLDSK-----QKHRVDFLQLMMNAHNNS 282

  Fly   294 ------APLSDEDIREEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSP 352
                  ..|||.:|..:...|:|.|::||:|.:||.||.::.||::|::||:||.:.|  ..|:|
Mouse   283 KDKDSHKALSDMEITAQSIVFIFAGYETTSSTLSFTLYCLATHPDIQKKLQEEIDETL--PNKAP 345

  Fly   353 VTLRDLGELKFMENVIKESLRLHPPVPMIGRWFAEDVEIRGKHIPAGTNFTMGIFVLLRDPEYFE 417
            .|...:.|:::::.|:.|:|||:|....:.|:..:|||:.|.:||.|:...:..:.|..||:::.
Mouse   346 PTYDTVMEMEYLDMVLNETLRLYPIGNRLERFCKKDVELNGVYIPKGSTVMIPSYALHHDPQHWP 410

  Fly   418 SPDEFRPERFDAD-VPQIHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLP 474
            .|:||:||||..: ...|.||.|:||..|||||||.:||.:.||..::|::::|...|
Mouse   411 EPEEFQPERFSKENKGSIDPYLYMPFGIGPRNCIGMRFAFMTMKLALTKVMQNFSFQP 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	121/449 (27%)
Cyp3a41a	NP_059092.2	CYP3A	67..493	CDD:410743	123/451 (27%)