Protein Alignment Cyp4d2 and cyp3c3

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001007401.2
• Gene: cyp3c3 / 492759
• ZFINID: ZDB-GENE-041114-102
• Length: 503
• Species: Danio rerio
• Alignment Length: 534
• Identity: 141/534 - (26%)
• Similarity: 245/534 - (45%)
• Gaps: 76/534 - (14%)

  Fly     2 LGVVGVLLLVAFATLLLWDFLW-----RRRGNGILPGPRPLPFLGNLLMYRGLDPEQIMDFVKKN 61
            |.|...|:.:.. |||....:|     ::.|   :|||||.||.|..|.|    .:...:|..:.
Zfish     7 LSVTWTLVFLVI-TLLYMYGVWPHGFFKKLG---IPGPRPWPFFGTFLSY----TKGFFNFDMEC 63

  Fly    62 QRKYGRLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLYKL---LNCWLGDGLLMSTGRKWH 123
            .:|||:::.::......:..||...|:.::..:.:.|..|..::   |...|.||:......:|.
Zfish    64 AKKYGKVWGIYDGRLPILMVTDLEMIKTIMVKECYSTFTNRREVNVDLAGPLADGISAVKDERWK 128

  Fly   124 GRRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIAETAMGTK 188
            ..|..::|.|....|::...|....:...::.:|.| |...|:.|..|:...:||::..::....
Zfish   129 RIRGTLSPYFTSGRLKEIFPIAMTHADRFIKNMQKR-DHEQPVKIKEVVAPYSLDVVTSSSFSVD 192

  Fly   189 INAQKNPNLPYVQAVND-------------------VTNILIKRFIHAWQRVDWIFRLTQPTEAK 234
            |::..||:.|:|..:.:                   :.|:|.|..|..:.|....|..|...:.|
Zfish   193 IDSINNPDDPFVTNIKNFLKFSLFSPLILFLTLFPSIANLLGKMGISVFSRSIMNFFYTALRKIK 257

  Fly   235 RQDKAIKVMHDFTENIIRERRETLVNNSKETTPEEEVNFLGQKRRMALLDVLLQSTIDGAPLSDE 299
            .:.|......||...:|:.:...  :.:|:||.|:.|.                      .|:|.
Zfish   258 DEHKDSNGRVDFLRLMIQNQIPD--DQAKDTTSEQPVK----------------------GLTDH 298

  Fly   300 DIREEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFM 364
            :|..:...|:..|::||::.:||.|:.::.:|:..::|.:||......|  :|::...|.::.::
Zfish   299 EILSQSFIFILGGYETTSTTLSFLLHNLATNPDCLEKLVEEIDKNFPLD--TPISYDALMKMDYL 361

  Fly   365 ENVIKESLRLHPPVPMIGRWFAEDVEIRGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERFDA 429
            |..|.||:||.|..|.:.|...:.||:.|..||..|...:..:||.|||:.::||.|||||||..
Zfish   362 EMSINESMRLLPTAPRLERVCKKTVELNGITIPKDTLVAIPTYVLNRDPQLWDSPQEFRPERFSP 426

  Fly   430 D-VPQIHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFEL-------LPLGPEPRHSMNIV 486
            : ..:...||::||..|||||||.:||::.:|..|.|||::|.|       :||...|      |
Zfish   427 ENKSEFLQYAFMPFGLGPRNCIGMRFALMIVKLLVVKLLQNFSLETCKETQIPLELTP------V 485

  Fly   487 LRSANGVHLGLKPR 500
            .:....:.|.|.||
Zfish   486 FQPKVPITLKLTPR 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	116/458 (25%)
cyp3c3	NP_001007401.2	cytochrome_P450	66..495	CDD:477761	118/461 (26%)