Protein Alignment Cyp4d2 and LOC4577452

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: XP_001230597.4
• Gene: LOC4577452 / 4577452
• VectorBaseID: AGAMI1_012198
• Length: 513
• Species: Anopheles gambiae
• Alignment Length: 495
• Identity: 142/495 - (28%)
• Similarity: 245/495 - (49%)
• Gaps: 46/495 - (9%)

  Fly     8 LLLVAFATLLLW-----DFLWRRRGNGILPGPRPL-PFLGNLLMYRGLDPEQIMDFVKKNQRKYG 66
            |||:.|..|.|:     .|.:..:    :|...|| |..||.|.:...:..:|...:.:..:...
Mosquito     4 LLLLGFGALSLYLYCKIKFKFAEK----IPCVEPLHPIFGNGLEFAQKNSYEIFKSLTRAYKDNK 64

  Fly    67 RLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLYKLLNCWLGDGLLMSTGRKWHGRRKIITP 131
            |::::.......:..|.|..|:.:::.|..:.|..:|..:.  :..|||.:...:|...||.:.|
Mosquito    65 RIFKLCFGPIPVICPTHPDLIQKIMTEQASMDKPFVYDFMR--VDHGLLTAQYDEWRVHRKALNP 127

  Fly   132 TFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIAETAMGTKINAQKNPN 196
            ||:.:||..|:.||....|.|:..::..|....|||:........|::|..|::|.|: .::...
Mosquito   128 TFNTRILNSFIPIFTDCVAKMIANMEKHAGDEKPINVLEFTSPCTLEMICRTSLGGKV-LEREGK 191

  Fly   197 LPYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQPTEAKRQDKAIKVMHDFTENIIRERR----ET 257
            ..:::.:..:.:.:..|..:|....|.::|.|:..:|:..  |.|:.:.||:.:|||:|    |.
Mosquito   192 QEFIEGLEIILHNVGLRMFNANLYPDIVYRNTRFYKAEMD--ARKICYAFTDKVIREKRAKFEEK 254

  Fly   258 LVN----NSKETT---------PEEEVNFLGQKRRMALLDVLLQSTIDGAPLSDEDIREEVDTFM 309
            |.|    |:..||         .:||.:.|..|:....:|.||....||.|.:.|:|.:.:.|.:
Mosquito   255 LRNAVDSNNNSTTADENGNVVFADEEDDMLSYKKPQIFVDQLLTIPNDGKPFTHEEITDHIYTMI 319

  Fly   310 FEGHDTT-TSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESLR 373
            ..|::|: |.|...||. ::.|||:|.|...||.::|.:|.:  .|...|.:::::|.|||||.|
Mosquito   320 AAGNETSATQAAHACLL-LAMHPEIQDRAAAEICELLADDVE--YTHETLKQMQYLERVIKESQR 381

  Fly   374 LHPPVPMIGRWFAEDVEIRGKHIPAGTNFTMGIFVLLRDPEYFE------SPDEFRPERFDADVP 432
            |.|...:.||.....:::....||.|....:.:|.|.|..|::.      .||.|.|||..|.
Mosquito   382 LCPVAAVYGRKTIGTIQLDEYVIPKGFILLLNVFALHRQKEFWGPNADKFDPDHFLPERVKAR-- 444

  Fly   433 QIHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFEL 472
              |||||:|||.|||.|||.::||:.:|..:|::|:::.|
Mosquito   445 --HPYAYLPFSGGPRGCIGSRYAMMSLKIILSQILKNYRL 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	127/431 (29%)
LOC4577452	XP_001230597.4	None