Protein Alignment Cyp4d2 and Cyp4e1

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_524771.1
• Gene: Cyp4e1 / 44632
• FlyBaseID: FBgn0015034
• Length: 531
• Species: Drosophila melanogaster
• Alignment Length: 540
• Identity: 210/540 - (38%)
• Similarity: 304/540 - (56%)
• Gaps: 64/540 - (11%)

  Fly     8 LLLVAFATLLLW-------DFLWRRRGNGILPGPRPLPFLGNLLMYRGLDPEQIMDFVKKNQRKY 65
            ::|.||..|.|:       ..|.|:|......||..||.:|| ....|..|.:|::.......:|
  Fly     3 IVLCAFLALPLFLVTYFELGLLRRKRMLNKFQGPSMLPLVGN-AHQMGNTPTEILNRFFGWWHEY 66

  Fly    66 GR-LYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLYKLLNCWLGDGLLMSTGRKWHGRRKII 129
            |: .:|.||.:...:..|:|:.:||:||||..|:|:::|.|.:.|||.|||.|||.|||..||:|
  Fly    67 GKDNFRYWIGYYSNIMVTNPKYMEFILSSQTLISKSDVYDLTHPWLGLGLLTSTGSKWHKHRKMI 131

  Fly   130 TPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIF----PVICLTALDIIAETAMGTKIN 190
            ||.|||.||:.|.|:.::.|...::||:..|||.   |||    ....|| ||:|.:||||..||
  Fly   132 TPAFHFNILQDFHEVMNENSTKFIDQLKKVADGG---NIFDFQEEAHYLT-LDVICDTAMGVSIN 192

  Fly   191 AQKNPNLPYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQPTEAKRQDKAIKVMHDFTENIIRERR 255
            |.:|.:...|||..|:|..:..|....|:|..::|...  .|.....|.:|.:.|||..||.:|.
  Fly   193 AMENRSSSVVQAFKDITYTIKMRAFSPWKRNKYLFHFA--PEYPEYSKTLKTLQDFTNEIIAKRI 255

  Fly   256 ETLVNNSKETTPEEEVNFLGQKRRMALLDVLLQSTIDGAPLSDEDIREEVDTFMFEGHDTTTSAI 320
            |...:..:.....:|.:    :::||.||.||.|.:||.||:.:::.|||.||||||||||||.:
  Fly   256 EVRKSGLEVGIKADEFS----RKKMAFLDTLLSSKVDGRPLTSQELYEEVSTFMFEGHDTTTSGV 316

  Fly   321 SFCLYEISRHPEVQQRLQQEIRDV-----LGEDRKSPVTLRDLGELKFMENVIKESLRLHPPVPM 380
            .|.:|.:||||:.|::|..|..||     ||.|    .|.:::..:|.::..|||:.||:|.||.
  Fly   317 GFAVYLLSRHPDEQEKLFNEQCDVMGASGLGRD----ATFQEISTMKHLDLFIKEAQRLYPSVPF 377

  Fly   381 IGRWFAEDVEIRGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERFDADVPQIHPYAYIPFSAG 445
            |||:..:|..|.|..:|.||...:|:.:|..:...|:.|.:|:|||||.:.|  .|:.|:|||||
  Fly   378 IGRFTEKDYVIDGDIVPKGTTLNLGLLMLGYNDRVFKDPHKFQPERFDREKP--GPFEYVPFSAG 440

  Fly   446 PRNCIGQKFAMLEMKSTVSKLLRHFELLP---------------LGPEPRH-------------- 481
            ||||||||||:||:|:.|||::|:||:||               ||.:|..
  Fly   441 PRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTLGLQPAEKKSRDAHNHKYDPI 505

  Fly   482 -SMNIVLRSANGVHLGLKPR 500
             |.::.|:|.||:||.:|.|
  Fly   506 LSASMTLKSENGLHLRMKQR 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	188/468 (40%)
Cyp4e1	NP_524771.1	CYP4	68..520	CDD:410721	187/467 (40%)