Protein Alignment Cyp4d2 and Cyp4a30b

DIOPT Version :9

• Sequence 1: NP_001284806.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: XP_006503285.1
• Gene: Cyp4a30b / 435802
• MGIID: 3717145
• Length: 510
• Species: Mus musculus
• Alignment Length: 520
• Identity: 173/520 - (33%)
• Similarity: 272/520 - (52%)
• Gaps: 46/520 - (8%)

  Fly     1 MLGVVGVLLLVAFATLLLWDFLWRRRGNGIL-------------PGPRPLPFLGNLLMYRGLDPE 52
            :.|:.|:|.:|:...|||   |..:.....|             |.|.|....||.|  :..|.:
Mouse    12 VFGIFGLLQVVSLLGLLL---LLLKSAQYYLHRQWLIKSLQQFPPAPPPQWLFGNTL--KDQDLQ 71

  Fly    53 QIMDFVKKNQRKYGRLYRVWILHQLAVFSTDPRDIEFVLS-SQQHITKNNLYKLLNCWLGDGLLM 116
            ||:..|:|....|.|.  :|..|...|. .||..::.:|. |...:.::  |.....|:|.|||:
Mouse    72 QILLCVEKFPSTYVRW--LWGNHARVVI-YDPDYMKVILGRSDPKVVRS--YSFFAPWIGYGLLL 131

  Fly   117 STGRKWHGRRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIA 181
            ..|:||...|:::||.||:.||:.:|.|......||:::.:...|...|:.|:..|.|..::.:.
Mouse   132 LNGKKWFQHRRMLTPAFHYDILKPYVGIMVDSVHVMLDKWEQLVDQDCPLEIYQDISLMTMETMM 196

  Fly   182 ETAMGTKINAQ----KNPNLPYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQPTEAKRQDKAIKV 242
            :.|...:.:.|    :| :..|::||.|:|:::..|..:.:.:.:.|:.|:  :..:....|.::
Mouse   197 KCAFSYQGSVQLEDCRN-SKSYIKAVEDLTHLIYLRVRNGFHQNNTIYSLS--SNGRSFYHACQI 258

  Fly   243 MHDFTENIIRERRETLVNNSKETTPEEEVNFLGQKRRMALLDVLL-QSTIDGAPLSDEDIREEVD 306
            .|..||.:||.|:..|.|       |.|:....:|:|:..||:|| ..|.||..|||||:|.|:|
Mouse   259 AHKHTERVIRMRKAQLQN-------EAELEKFRKKKRLDFLDILLFAQTEDGKSLSDEDVRAEMD 316

  Fly   307 TFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKES 371
            |||||||:||.|.||:..|.::.|||.|||.::|::.:||..  :.|||..|.::.:....|||:
Mouse   317 TFMFEGHNTTASGISWIFYALATHPEHQQRCREEVKSILGNG--TSVTLNHLDQMPYTTMCIKEA 379

  Fly   372 LRLHPPVPMIGRWFAEDVEI-RGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERFDADVPQIH 435
            |||:||:|...|..:..|.. .|..:|.|...|:..:.|..:|....:.:.|.|.||....|: .
Mouse   380 LRLYPPIPGASRELSSPVTFPDGCSLPKGFLVTLSFYGLHHNPRLRPNAEVFDPSRFAPGAPR-Q 443

  Fly   436 PYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLPLGPE--PRHSMNIVLRSANGVHLGLK 498
            .:|::|||||.|||||::|.|.|:|..|:..|..||||| .|.  |.....|||:|.||::|..|
Mouse   444 THAFLPFSAGTRNCIGKQFTMNELKVAVALTLLRFELLP-DPTRVPILVSKIVLKSKNGIYLHTK 507

  Fly   499  498
            Mouse   508  507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_001284806.1	p450	32..495	CDD:278495	162/471 (34%)
Cyp4a30b	XP_006503285.1	p450	59..504	CDD:365848	159/465 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845103
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.650