Protein Alignment Cyp4d2 and Cyp12a4

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Alignment Length: 501
• Identity: 115/501 - (22%)
• Similarity: 220/501 - (43%)
• Gaps: 100/501 - (19%)

  Fly    22 LWRRRGNGILPGPRPLPFLGNLLMYRGLDPEQIMDFVKKNQRKYGRLYRV-WILHQLAVFST-DP 84
            :|.......:||.:          |:.:   ::|:..:..::.||.::.: .|:......|| :|
  Fly    55 MWALSMKMSMPGGK----------YKNM---ELMEMFEAMRQDYGDIFFMPGIMGNPPFLSTHNP 106

  Fly    85 RDIEFVLSSQQHITKN--NLYKLL--------NCWLG-DGLLMSTGRKWHGRRKIITPT------ 132
            :|.|.|..: :.:..|  ..|.||        :.:.| .|::.:.|:.|...|.::.|.
  Fly   107 QDFEVVFRN-EGVWPNRPGNYTLLYHREEYRKDFYQGVMGVIPTQGKPWGDFRTVVNPVLMQPKN 170

  Fly   133 --FHFKILEQFVEIFDQQSAVM--VEQLQSRADGMTPINIFPVICLTALDIIAETAMGTKINAQK 193
              .::|.:.|..:.|.|:...:  .:.|::..|.:..||.:      .|:.::..|:..::...|
  Fly   171 VRLYYKKMSQVNQEFVQRILELRDPDTLEAPDDFIDTINRW------TLESVSVVALDKQLGLLK 229

  Fly   194 NPN-----LPYVQAVND--VTNILIKRFIHAWQRVDWIFRLTQPTEAKRQDKAIKVMHDFTENII 251
            |.|     |.....:::  :.:|.::.....|       |..:..:.||..:|:..:.:.|...:
  Fly   230 NSNKESEALKLFHYLDEFFIVSIDLEMKPSPW-------RYIKTPKLKRLMRALDGIQEVTLAYV 287

  Fly   252 RERRETLVNNSKE--TTPEEEVNFLGQKRRMALLDVLLQSTIDGAPLSDEDIREEVDTFM----- 309
            .|..|.|...:||  ..||.|         .::|:.||:            :..:|.|.|
  Fly   288 DEAIERLDKEAKEGVVRPENE---------QSVLEKLLK------------VDRKVATVMAMDML 331

  Fly   310 FEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESLRL 374
            ..|.|||:|..:..|..::::||.|.||::|:..|| .::.|..|...:..:.::...||||.||
  Fly   332 MAGVDTTSSTFTALLLCLAKNPEKQARLREEVMKVL-PNKNSEFTEASMKNVPYLRACIKESQRL 395

  Fly   375 HPPVPMIGRWFAEDVEIRGKHIPAGTNFT-MGIFVLLRDPEYFESPDEFRPERF-----DA---- 429
            ||.:....|..|.|..:.|..:||||... :.:..|.|| |||....||.|||:     |:
  Fly   396 HPLIVGNARVLARDAVLSGYRVPAGTYVNIVPLNALTRD-EYFPQASEFLPERWLRSPKDSESKC 459

  Fly   430 ---DVPQIHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFEL 472
               ::...:|:.::||..|||.|:|::...:|::...::|:|:|.:
  Fly   460 PANELKSTNPFVFLPFGFGPRMCVGKRIVEMELELGTARLIRNFNV 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	109/457 (24%)
Cyp12a4	NP_650783.2	CYP24A1-like	82..528	CDD:410677	110/461 (24%)