Protein Alignment Cyp4d2 and Cyp6d5

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_650327.1
• Gene: Cyp6d5 / 41706
• FlyBaseID: FBgn0038194
• Length: 508
• Species: Drosophila melanogaster
• Alignment Length: 574
• Identity: 133/574 - (23%)
• Similarity: 236/574 - (41%)
• Gaps: 146/574 - (25%)

  Fly     4 VVGVLLLVAFATLLL----WDF-LWRRRGNGILPGPRPLPFLGNLLMYRGLDPEQIMDFVKKNQR 63
            ::|:.||:|..|||.    |.| .|.|:|         .|..|..:.:..|:.      |.|.:|
  Fly     1 MIGIYLLIAAVTLLYVYLKWTFSYWDRKG---------FPSTGVSIPFGALES------VTKGKR 50

  Fly    64 KYGR---------------LY---RVWILHQLAVFSTDPRDIEFVLSSQQHI---TKNNLYKLLN 107
            .:|.               ||   |..:|.:.|..:.|....:|.....:.:   .||:.
  Fly    51 SFGMAIYDMYKSTKEPVIGLYLTLRPALLVRDAQLAHDVLVKDFASFHDRGVYVDEKNDP----- 110

  Fly   108 CWLGDGLLMSTGRKWHGRRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSR--ADGMTPINIFP 170
              :...|....|..|...|..:||:|....|:...|..|.....:|:.::.:  |:|...:.:..
  Fly   111 --MSASLFQMEGASWRALRNKLTPSFTSGKLKAMFETSDSVGDKLVDSIRKQLPANGAKELELKK 173

  Fly   171 VICLTALDIIAETAMGTKINAQKNPNLPYVQAV------NDVTNIL----------IKRFIHAWQ 219
            ::...|:||||.|..|..:::..:||..: |.:      |::.:|:          :::|   :.
  Fly   174 LMATYAIDIIATTIFGLDVDSFADPNNEF-QIISKKVNRNNIEDIIRGTSSFLYPGLEKF---FV 234

  Fly   220 RVDWIFRLTQPTEAKRQDKAIKVMHDFTENIIRERRETLVNNSKETTPEEEVNFLGQKRRMALLD 284
            ::.|           :|:..             ||...|.|.:.:.  .|:.|.:    |..||.
  Fly   235 KIGW-----------KQEAT-------------ERMRELSNRTVDL--REQNNIV----RKDLLQ 269

  Fly   285 VLLQ-----------------STIDGAPLSDED-IREEVDTFMFEGHDTTTSAISFCLYEISRHP 331
            :|||                 ||.:|.....:| |..::..|...|::||.|..||.|||::::|
  Fly   270 LLLQLRNQGKINTDDNIWSAESTKNGVKSMSKDLIAGQLFLFYVAGYETTASTTSFTLYELTQNP 334

  Fly   332 EVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESLRLHPPVPMIGRWFAEDVEIRGKH- 395
            ||.::.::::|..: |.....:|...:.::|::|..|.|:.|.:|.:|::.|...:|..:....
  Fly   335 EVMEKAKEDVRSAI-EKHGGKLTYDAISDMKYLEACILETARKYPALPLLNRICTKDYPVPDSKL 398

  Fly   396 -IPAGTNFTMGIFVLLRDPEYFESPDEFRPERFDADVPQIHPYAYIPFSAGPRNCIGQKFAMLEM 459
             |..||...:.:..:.||.|||..|..::|||:..:.......||:||..|||.|||.:...:.:
  Fly   399 VIQKGTPIIISLIGMHRDEEYFPDPLAYKPERYLENGKDYTQAAYLPFGEGPRMCIGARMGKVNV 463

  Fly   460 KSTVSKLLRHFEL---------------LPLGPEPRHSMNIVLRSANGVHLGLK 498
            |..::|:|.:|:|               :||.|          :|...|.|.||
  Fly   464 KIAIAKVLSNFDLEIRKEKCEIEFGVYGIPLMP----------KSGVPVRLSLK 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	112/502 (22%)
Cyp6d5	NP_650327.1	CYP6-like	63..501	CDD:410679	110/489 (22%)