Protein Alignment Cyp4d2 and Cyp12c1

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_649052.1
• Gene: Cyp12c1 / 40037
• FlyBaseID: FBgn0036806
• Length: 524
• Species: Drosophila melanogaster
• Alignment Length: 503
• Identity: 125/503 - (24%)
• Similarity: 207/503 - (41%)
• Gaps: 114/503 - (22%)

  Fly    31 LPGPRPLPFLGNLLMYRG---------LDPEQIMDFVKKNQRKYGRLYRVWILHQL--AVFSTDP 84
            ||||.      ...::||         |..:.:|...||   ::|.:..:..|..:  .||:.:.
  Fly    44 LPGPT------RWQLFRGFQKGGEYHQLGMDDVMRLYKK---QFGDICLIPGLFGMPSTVFTFNV 99

  Fly    85 RDIEFVLSSQ---------------QHITKNNLYKLLNCWLGDGLLMSTGRKWHGRRKIITP--- 131
            ...|.|..::               ::..|:..:|  || :|   |...|.:|...|..:.|
  Fly   100 ETFEKVYRTEGQWPVRGGAEPVIHYRNKRKDEFFK--NC-MG---LFGNGAEWGKNRSAVNPVLM 158

  Fly   132 -----TFHFKILE----QFV----EIFDQQSAVMVEQLQSRADGMTPIN--IFPVICLTALDIIA 181
                 ..:.|.::    |||    ||.|::|.      :...|.|..||  .|..:...|||
  Fly   159 QHRNVAIYLKPMQRVNRQFVNRIREIRDKESQ------EVPGDFMNTINHLTFESVATVALD--- 214

  Fly   182 ETAMGTKINAQKNPNLPYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQPTEAKRQDKAIKVMHDF 246
             ..:|  :..:.||. |....:.....:|:..|.....|.. ::|.......|:..:|:..:.|.
  Fly   215 -RELG--LLREANPP-PEASKLFKNIEVLMDSFFDLGVRPS-LYRYIPTPTYKKFSRAMDEIFDT 274

  Fly   247 TENIIRERRETLVNNSKETTPEEEVNFLGQ----KRRMAL---LDVLLQSTIDGAPLSDEDIREE 304
            ....:.:..|.:...|.:....:..:.|.|    .|::|:   :|:|:
  Fly   275 CSMYVNQAIERIDRKSSQGDSNDHKSVLEQLLQIDRKLAVVMAMDMLM----------------- 322

  Fly   305 VDTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIK 369
                  .|.|||::|||..|..::::||.||||::|:...| ....|..|:.|:..|.::..|||
  Fly   323 ------GGVDTTSTAISGILLNLAKNPEKQQRLREEVLSKL-TSLHSEFTVEDMKSLPYLRAVIK 380

  Fly   370 ESLRLHPPVPMIGRWFAEDVEIRGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERF------- 427
            |||||:|......|....||.:.|..||.||...|....||:|...:....||.|||:
  Fly   381 ESLRLYPVTFGNARSAGADVVLDGYRIPKGTKLLMTNSFLLKDDRLYPRAKEFIPERWLRRKDDD 445

  Fly   428 DADV---PQIHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFEL 472
            .:||   ..::.:.|:||..|||.|:|::...|||:.||:.|:|:|.:
  Fly   446 KSDVLMNKDLNAFIYLPFGFGPRMCVGKRIVDLEMELTVANLVRNFHI 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	115/459 (25%)
Cyp12c1	NP_649052.1	CYP24A1-like	76..516	CDD:410677	116/465 (25%)