Protein Alignment Cyp4d2 and Cyp12b2

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_611370.2
• Gene: Cyp12b2 / 37163
• FlyBaseID: FBgn0034387
• Length: 535
• Species: Drosophila melanogaster
• Alignment Length: 516
• Identity: 121/516 - (23%)
• Similarity: 217/516 - (42%)
• Gaps: 65/516 - (12%)

  Fly    20 DFLWRR-RGNGILPGPRPLPFLGNLLMYRGLDPEQIMDFVKKNQRKYGRLYRV--WILHQLAVFS 81
            |..|:: |..|.:|||..|..|...:....|....::...:..:..||.:|.:  .:....|||:
  Fly    44 DEKWQQARSFGEIPGPSLLRMLSFFMPGGALRNTNLIQMNRLMREMYGDIYCIPGMMGKPNAVFT 108

  Fly    82 TDPRDIEFV---------------LSSQQHITKNNLYKLLNCWLGDGLLMSTGRKWHGRRKIITP 131
            .:|.|.|..               |:..:.|.:.:::|.:.     ||....|::|...|..:.|
  Fly   109 YNPDDFEMTYRNEGVWPIRIGLESLNYYRKIHRPDVFKGVG-----GLASDQGQEWADIRNKVNP 168

  Fly   132 TFHFKI--LEQFVEIFDQQSAVMVEQLQSRADGMT---PINIFPVICLTALDIIAETAMGTKIN- 190
            .. .|:  :.|.:...||.|...:::|:::.:..|   ..:....:.:.|.:.|:..|:.|::.
  Fly   169 VL-MKVQNVRQNLPQLDQISKEFIDKLETQRNPETHTLTTDFHNQLKMWAFESISFVALNTRMGL 232

  Fly   191 AQKNPNLPYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQPTEAKRQDKAIKVMHDFTENIIRERR 255
            ...||:....:....:.:.....|....|...|.|..|  ...|:..|....:.|.|.|.|....
  Fly   233 LSDNPDPNADRLAKHMRDFFNYSFQFDVQPSIWTFYKT--AGFKKFLKTYDNITDITSNYIETAM 295

  Fly   256 ETLVNNSKETTPEEEVNFLGQKRRMALLDVLLQSTIDGAPLSDEDIREEVDTFMFEGHDTTTSAI 320
            .....|....|.......|...:::|:..|:                    ..:..|.|||:||.
  Fly   296 RGFGKNDDGKTKCVLEQLLEHNKKVAVTMVM--------------------DMLMAGIDTTSSAC 340

  Fly   321 SFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESLRLHPPVPMIGRWF 385
            ...||.::|:|..|::|::|:..:| ...|..:|.::...:.::...|||.||:....|...|..
  Fly   341 LTILYHLARNPSKQEKLRRELLRIL-PTTKDSLTDQNTKNMPYLRACIKEGLRITSITPGNFRIT 404

  Fly   386 AEDVEIRGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERF-DADV-PQI---------HPYAY 439
            .:|:.:.|..:|.||...||:..|..|.:||....||.|||: .:|: |.|         :|:.|
  Fly   405 PKDLVLSGYQVPRGTGVLMGVLELSNDDKYFAQSSEFIPERWLKSDLAPDIQACPAARTRNPFVY 469

  Fly   440 IPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLPLGPEP-RHSMNIVLRSANGVHLGLKP 499
            :||..|||.|||::.|.||:::.:.:|||.:::..|...| .:...|:|.....:...|:|
  Fly   470 LPFGFGPRTCIGKRIAELEIETLLVRLLRSYKVSWLPETPIEYESTIILSPCGDIRFKLEP 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	108/463 (23%)
Cyp12b2	NP_611370.2	CYP24A1-like	87..525	CDD:410677	109/466 (23%)