Protein Alignment Cyp4d2 and Cyp6a8

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_523749.2
• Gene: Cyp6a8 / 36666
• FlyBaseID: FBgn0013772
• Length: 506
• Species: Drosophila melanogaster
• Alignment Length: 560
• Identity: 120/560 - (21%)
• Similarity: 226/560 - (40%)
• Gaps: 135/560 - (24%)

  Fly     7 VLLLVAFATLLLWDF-------LWRRRGNGILPGPRPLPFLGNLLMYRGLDP--------EQIMD 56
            :|..||.|.|.:..:       .::|||         :||:...|:...::.        |...|
  Fly     6 ILFQVAVALLAILTYYIHRKLTYFKRRG---------IPFVAPHLIRGNMEELQKTKNIHEIFQD 61

  Fly    57 FVKKNQRKYGRLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLYKLLNCWLGDGLLMS---- 117
            ...|.:.........:.....|.|..|           ..:.|..|.|..:.:...|:..:
  Fly    62 HYNKFRESKAPFVGFFFFQSPAAFVID-----------LELAKQILIKDFSNFSNKGIFYNEKDD 115

  Fly   118 ---------TGRKWH------------GRRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRAD 161
                     .|.:|.            |:.|::.||        .|.:.::...||.|::...
  Fly   116 PISAHLFNLDGAQWRLLRNKLSSTFTSGKMKLMYPT--------VVSVANEFMTVMHEKVPKN-- 170

  Fly   162 GMTPINIFPVICLTALDIIAETAMGTKINAQKNPNLPYV-----QAVNDVTNILIKRFIHAWQRV 221
              :.:.|..::....:|:|...|.|.:.|:.::....::     ..|:.....|:..|:.::.::
  Fly   171 --SVLEIRDLVARFTVDVIGTCAFGIQCNSLRDEKAEFLYFGKRSLVDKRHGTLLNGFMRSYPKL 233

  Fly   222 --------------DWIFRLTQPTEAKRQDKAIKVMHDFTENIIRERRETLVNNSKETTPEEEVN 272
                          ::..|:...|.|.|:.:.|| .:||.:.:|.      :.|.||.|.|..
  Fly   234 ARKLGMVRTAPHIQEFYSRIVTETVAVREKEHIK-RNDFMDMLIE------LKNQKEMTLENG-- 289

  Fly   273 FLGQKRRMALLDVLLQSTIDGAPLSDEDIREEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRL 337
                       ||:...|:       |::..:...|...|.:|::|.:.|.|||::::|::|.::
  Fly   290 -----------DVVRGLTM-------EEVLAQAFVFFIAGFETSSSTMGFALYELAKNPDIQDKV 336

  Fly   338 QQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESLRLHPPVPMIGRWFAEDVEIRGKH----IPA 398
            :.|:.:|: |......|.....:||::..|:.|:|||:..||.:.|..|:...:.| |    |.|
  Fly   337 RAEVEEVI-EQHDQNFTYECTKDLKYLNQVLDETLRLYTIVPNLDRMAAKRYVVPG-HPNFVIEA 399

  Fly   399 GTNFTMGIFVLLRDPEYFESPDEFRPERFDADVPQIHP-YAYIPFSAGPRNCIGQKFAMLEMKST 462
            |.:..:....:..||..:..|.|||||||..:.....| .|::||..|||||||.:|..::.:..
  Fly   400 GQSVIIPSSAIHHDPSIYPEPFEFRPERFSPEESAGRPSVAWLPFGDGPRNCIGLRFGQMQARIG 464

  Fly   463 VSKLLRHFELL-------PLGPEPRHSMNIVLRSANGVHL 495
            ::.|:|:|:..       ||..:|:   :.||...:|::|
  Fly   465 LALLIRNFKFSTCSKTPNPLVYDPK---SFVLGVKDGIYL 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	105/484 (22%)
Cyp6a8	NP_523749.2	CYP6-like	70..500	CDD:410679	105/484 (22%)