Protein Alignment Cyp4d2 and Cyp6a21

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_611003.2
• Gene: Cyp6a21 / 36665
• FlyBaseID: FBgn0288232
• Length: 504
• Species: Drosophila melanogaster
• Alignment Length: 571
• Identity: 122/571 - (21%)
• Similarity: 234/571 - (40%)
• Gaps: 158/571 - (27%)

  Fly     1 MLGVVGVLLLVAFATLLLWDFLWRRRGNGILPGPRPLPFLGNLLMYRGLDPEQIMDFVKKNQRKY 65
            :|.:||.||:...:|:..|..|      || |...|...:|::                |..|..
  Fly    11 LLALVGYLLMKWRSTMRHWQDL------GI-PCEEPHILMGSM----------------KGVRTA 52

  Fly    66 GRLYRVWILHQLAVFSTDP--------RDIEFVLSSQQHITKNNLYKLLNCWLGDG--------- 113
            .....:|..:......:.|        |...|||.:.  :.|..|.|..|.:...|
  Fly    53 RSFNEIWTSYYNKFRGSGPFAGFYWFRRPAVFVLETS--LAKQILIKEFNKFTDRGFFHNPEDDP 115

  Fly   114 ----LLMSTGRKWH------------GRRKIITPTFHFKILEQFVEIFDQQSA----VMVEQLQS 158
                |.:..|:||.            |:.|.:.||. .|:..:|.::|.|..|    |.|.:|.:
  Fly   116 LSGQLFLLDGQKWRTMRNKLSSTFTSGKMKYMFPTV-VKVANEFTDVFGQNVAKSPVVEVRELLA 179

  Fly   159 RADGMTPINIFPVICLTALDIIAETAMGTKINAQKNPNLPY-----------------VQAVNDV 206
            |               ...|:|...|.|.:.::.|:|:..:                 :..||..
  Fly   180 R---------------FTTDVIGTCAFGIECSSLKDPDAEFREMGRRSLTEQRLGPVGIGFVNSF 229

  Fly   207 TNILIKRFIHAWQRVD----WIFRLTQPTEAKRQDKAIKVMHDFTENII-RERRETLVNNSKETT 266
            .|  :.|.:|.....:    :..|:.:.|.|.|:...|: .:||.:.:| .:.:..:|:.|.|:
  Fly   230 PN--LARRLHMKMTAEPIERFFMRIVRETVAFREQNNIR-RNDFMDQLIDLKNKPLMVSQSGES- 290

  Fly   267 PEEEVNFLGQKRRMALLDVLLQSTIDGAPLSDEDIREEVDTFMFEGHDTTTSAISFCLYEISRHP 331
                ||                       |:.|:|..:...|...|.:|:::.:.|.|||::::.
  Fly   291 ----VN-----------------------LTIEEIAAQAFVFFAAGFETSSTTMGFALYELAQNQ 328

  Fly   332 EVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESLRLHPPVPMIGRWFAEDVEIRG--K 394
            ::|.|:::|.::|: |.....:....:.:|.:::.|:.|:|||:..:|::.|...||.|:.|  |
  Fly   329 DIQNRVRKECQEVI-EKCNGELNYESMKDLVYLDQVVSETLRLYTVLPVLNRECLEDYEVPGHPK 392

  Fly   395 HIPAGTNFTMGIFVLL------RDPEYFESPDEFRPERFDAD-VPQIHPYAYIPFSAGPRNCIGQ 452
            ::     ...|:.||:      ||.:.:.:|:.|.|:.|..: |.:.....::||..|||||||.
  Fly   393 YV-----IKKGMPVLIPCGAMHRDEKLYANPNTFNPDNFSPERVKERDSVEWLPFGDGPRNCIGM 452

  Fly   453 KFAMLEMKSTVSKLLRHFEL-------LPLGPEPRHSMNIVLRSAN-GVHL 495
            :|..::.:..::.|::.|:.       :|:    .::..:.|.::| |::|
  Fly   453 RFGQMQARIGLALLIKDFKFSVCEKTTIPM----TYNKEMFLIASNSGIYL 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	106/504 (21%)
Cyp6a21	NP_611003.2	CYP6-like	68..498	CDD:410679	105/488 (22%)