Protein Alignment Cyp4d2 and Cyp6a14

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_610389.3
• Gene: Cyp6a14 / 35835
• FlyBaseID: FBgn0033302
• Length: 509
• Species: Drosophila melanogaster
• Alignment Length: 567
• Identity: 143/567 - (25%)
• Similarity: 235/567 - (41%)
• Gaps: 140/567 - (24%)

  Fly     2 LGVVGVLLLVAFATLLLWDFLWRRRGNGILPGPRPLPFLGNLLMYRGLDPEQIMDFVKK------ 60
            :.:|||:|.:|::..:.....|:|:|   :|...|||.:||:   ||:        |||
  Fly     5 IALVGVVLGLAYSLHIKIFSYWKRKG---VPHETPLPIVGNM---RGI--------VKKYHFRDI 55

  Fly    61 NQRKY------GRLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLYKLLNCWLGDG------ 113
            |||.|      |.:..:::..:.....|   |::|:        |..:.|..:.:...|
  Fly    56 NQRIYKKFKGQGPIAGMYMFFKRTALIT---DLDFI--------KQVMIKDFSYFQDRGAFTNPR 109

  Fly   114 -------LLMSTGRKWHGRRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTP------ 165
                   |....|.:|...|..:||.|....::       |.|.|:|:......|.|..
  Fly   110 DDPLTGHLFALEGEEWRAMRHKLTPVFTSGKIK-------QMSKVIVDVGLRLGDAMDKAVKEAK 167

  Fly   166 -----INIFPVICLTALDIIAETAMGTKINAQKNPNLPYVQAVNDV-----TNILIKRFIHAWQR 220
                 :.|..:......|:|...|.|.:.|:.::|:..:.|...::     .:.|::.||....|
  Fly   168 VEEGNVEIKDLCARFTTDVIGSCAFGLECNSLQDPSAEFRQKGREIFTRRRHSTLVQSFIFTNAR 232

  Fly   221 VDWIFR-------LTQ-------PTEAKRQDKAIKVMHDFTENIIRERRETLVNNSKETTPEEEV 271
            :....|       |||       .|...|....|| .:||.|.:|..|.|           ::|.
  Fly   233 LARKLRIKVLPDDLTQFFMSTVKNTVDYRLKNGIK-RNDFIEQMIELRAE-----------DQEA 285

  Fly   272 NFLGQKRRMALLDVLLQSTIDGAPLSD----EDIREEVDTFMFEGHDTTTSAISFCLYEISRHPE 332
            ...||                |..||.    |.:..:...|...|.:|::|.:|.||||::..|:
  Fly   286 AKKGQ----------------GIDLSHGLTLEQMAAQAFVFFVAGFETSSSTMSLCLYELALQPD 334

  Fly   333 VQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESLRLHPPVPMIGRWFAEDVEIRGKHIP 397
            :||||::||..||.......:....|.::.:::.|:.|:||.||.:|.:.|...:|.:|....|.
  Fly   335 IQQRLREEIESVLANVDGGELNYDVLAQMTYLDQVLSETLRKHPLLPHLIRETTKDYQIPNSDIV 399

  Fly   398 AGTNFTMGIFVLL------RDPEYFESPDEFRPERFD-ADVPQIHPYAYIPFSAGPRNCIGQKFA 455
                ...||..|:      .|||.:..|::|.|.||| .:|...||.||:||..|||||||.:|.
  Fly   400 ----LDKGILALIPVHNIHHDPEIYPEPEKFDPSRFDPEEVKNRHPMAYLPFGDGPRNCIGLRFG 460

  Fly   456 MLEMKSTVSKLLRHFEL-------LPLGPEPRHSMNIVLRSANGVHL 495
            .::.|..:..|||.|:.       :||....:   :.:|.:.:|::|
  Fly   461 KIQAKIGLVSLLRRFKFSVSNRTDVPLIFSKK---SFLLTTNDGIYL 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	119/489 (24%)
Cyp6a14	NP_610389.3	CYP6-like	65..503	CDD:410679	119/490 (24%)