Protein Alignment Cyp4d2 and Cyp4d1

DIOPT Version :9

• Sequence 1: NP_001284806.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Alignment Length: 512
• Identity: 224/512 - (43%)
• Similarity: 320/512 - (62%)
• Gaps: 14/512 - (2%)

  Fly     1 MLGVVGVLLLVA-FATLLLWDFLWRRRGNGI--LPGPRPLPFLGNLLMYRGLDPEQIMDFVKKNQ 62
            |..|:|.:|..| |..|||:...::|..:.|  :|||..||.:|:...:.|..|.:::..:.:..
  Fly     1 MFLVIGAILASALFVGLLLYHLKFKRLIDLISYMPGPPVLPLVGHGHHFIGKPPHEMVKKIFEFM 65

  Fly    63 RKYGR--LYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLYKLLNCWLGDGLLMSTGRKWHGR 125
            ..|.:  :.:||:..:|.|...:|:|:|.||.:.:...|...||.|..||.:|||:|.|||||.|
  Fly    66 ETYSKDQVLKVWLGPELNVLMGNPKDVEVVLGTLRFNDKAGEYKALEPWLKEGLLVSRGRKWHKR 130

  Fly   126 RKIITPTFHFKILEQFVEIFDQQSAVMVEQL-QSR-ADGMTPINIFPVICLTALDIIAETAMGTK 188
            ||||||.||||||:||||:|::.|..::..: |.| ..|.:..:::..|.|..:|.|.|||||..
  Fly   131 RKIITPAFHFKILDQFVEVFEKGSRDLLRNMEQDRLKHGDSGFSLYDWINLCTMDTICETAMGVS 195

  Fly   189 INAQKNPNLPYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQPTEAKRQDKAIKVMHDFTENIIRE 253
            ||||.|.:..|||||..::.:|.||..:...|.|..:.||....|::  ||:.|:|.|||.||.:
  Fly   196 INAQSNADSEYVQAVKTISMVLHKRMFNILYRFDLTYMLTPLARAEK--KALNVLHQFTEKIIVQ 258

  Fly   254 RRETLVNNSKETTPEEEVNFLGQKRRMALLDVLLQSTIDGAPLSDEDIREEVDTFMFEGHDTTTS 318
            |||.|:..........:...:|.||:||.||:|||||:|..|||:.|||||||||||||||||:|
  Fly   259 RREELIREGSSQESSNDDADVGAKRKMAFLDILLQSTVDERPLSNLDIREEVDTFMFEGHDTTSS 323

  Fly   319 AISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESLRLHPPVPMIGR 383
            |:.|..|.|:.|||.|::..:|||.|:|.|:.:||:...|.:|.:::..:||:||::|.||::||
  Fly   324 ALMFFFYNIATHPEAQKKCFEEIRSVVGNDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPLLGR 388

  Fly   384 WFAEDVEIRGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERFD--ADVPQIHPYAYIPFSAGP 446
            ...||.||.||.||||||..:....|.|..|.|..|:.|:|||||  ....:::|||||||||||
  Fly   389 KVLEDCEINGKLIPAGTNIGISPLYLGRREELFSEPNIFKPERFDVVTTAEKLNPYAYIPFSAGP 453

  Fly   447 RNCIGQKFAMLEMKSTVSKLLRHFELLPLGPE---PRHSMNIVLRSANGVHLGLKPR 500
            ||||||||||||:|:.|:.:|||:|:..:|..   |.....::||:...:...::.|
  Fly   454 RNCIGQKFAMLEIKAIVANVLRHYEVDFVGDSSEPPVLIAELILRTKEPLMFKVRER 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_001284806.1	p450	32..495	CDD:278495	212/471 (45%)
Cyp4d1	NP_476907.2	p450	35..507	CDD:278495	212/473 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449043
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	1	0.900	-	-		E33208_3B9GY
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28797
OrthoDB	1	1.010	-	-		D10482at33392
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
	11	10.910