Protein Alignment Cyp4d2 and cyp26a1

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_571221.2
• Gene: cyp26a1 / 30381
• ZFINID: ZDB-GENE-990415-44
• Length: 492
• Species: Danio rerio
• Alignment Length: 495
• Identity: 122/495 - (24%)
• Similarity: 217/495 - (43%)
• Gaps: 63/495 - (12%)

  Fly     4 VVGVLLLVAFATLLLWDFLWRRR-----GNGILPGPRPLPFLG---NLLMYRGLDPEQIMDFVKK 60
            |:.|||.:  |.:.||:.|..||     .:.:.||...|||:|   .|::.|       ..|::.
Zfish    15 VLPVLLFL--AAVKLWEMLMIRRVDPNCRSPLPPGTMGLPFIGETLQLILQR-------RKFLRM 70

  Fly    61 NQRKYGRLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLYKLLNCWLGDGLLMST-GRKWHG 124
            .::|||.:|:..:.....|......::..:|..:..:........:...||...|.:. |.:...
Zfish    71 KRQKYGCIYKTHLFGNPTVRVMGADNVRQILLGEHKLVSVQWPASVRTILGSDTLSNVHGVQHKN 135

  Fly   125 RRKIITPTFHFKILEQFVEIFDQQ--SAVMVEQLQSRADGMTPINIFPVICLTALDIIAETAMGT 187
            ::|.|...|....||.::.:..|:  ||:. |.||..    :.:.::|.:......|.....:|.
Zfish   136 KKKAIMRAFSRDALEHYIPVIQQEVKSAIQ-EWLQKD----SCVLVYPEMKKLMFRIAMRILLGF 195

  Fly   188 KINAQKNPNLPYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQPTEAK-----RQDKAIKVMHDFT 247
            :....|......|:|..:    :||.          :|.|  |.:..     |..:|...:|...
Zfish   196 EPEQIKTDEQELVEAFEE----MIKN----------LFSL--PIDVPFSGLYRGLRARNFIHSKI 244

  Fly   248 ENIIRERRETLVNNSKETTPEEEVNFLGQKRRMALLDVLLQSTIDGAPLSDEDIREEVDTFMFEG 312
            |..||::.:...|.::            ||.:.||..::..|.....|.|.:.::|.....:|.|
Zfish   245 EENIRKKIQDDDNENE------------QKYKDALQLLIENSRRSDEPFSLQAMKEAATELLFGG 297

  Fly   313 HDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSP---VTLRDLGELKFMENVIKESLRL 374
            |:||.|..:..:..:..:.||.|::::|:::.:.....:|   :::..|.:||:...||||:||:
Zfish   298 HETTASTATSLVMFLGLNTEVVQKVREEVQEKVEMGMYTPGKGLSMELLDQLKYTGCVIKETLRI 362

  Fly   375 HPPVPMIGRWFAEDVEIRGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERF-DADVPQIHPYA 438
            :||||...|...:..|:.|..||.|.|....|.......:.|.:.|||:|||| ...:.....:.
Zfish   363 NPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVADVFPNKDEFQPERFMSKGLEDGSRFN 427

  Fly   439 YIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFE-LLPLGP 477
            ||||..|.|.|:|::||.:.:|..:.:|.:|.. :|..||
Zfish   428 YIPFGGGSRMCVGKEFAKVLLKIFLVELTQHCNWILSNGP 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	101/425 (24%)
cyp26a1	NP_571221.2	CYP26A1	55..486	CDD:410731	107/453 (24%)