Protein Alignment Cyp4d2 and Cyp4f18

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001028858.2
• Gene: Cyp4f18 / 290623
• RGDID: 1305261
• Length: 524
• Species: Rattus norvegicus
• Alignment Length: 529
• Identity: 185/529 - (34%)
• Similarity: 275/529 - (51%)
• Gaps: 67/529 - (12%)

  Fly     7 VLLLVAFATLLLWDFLWRRRGNGILPG--------------PRPLPFLGNLLMYRGL--DPEQIM 55
            :||||..:.||.:          |||.              |:| |....|..:.||  ..|:.:
  Rat    21 LLLLVGASCLLAY----------ILPQVYAVFENSRRLRRFPQP-PTRNWLFGHLGLIQSSEEGL 74

  Fly    56 DFVKKNQRKYGRLYRVW---------ILHQ-------LAVFSTDPRDIEFVLSSQQHITKNNLYK 104
            .:::...|.:..:...|         |.|.       ||..|..|:|..|             |:
  Rat    75 LYIQSLSRTFRDVCCWWVGPWHPVIRIFHPAFIKPVILAPASVAPKDRVF-------------YR 126

  Fly   105 LLNCWLGDGLLMSTGRKWHGRRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRA-DGMTPINI 168
            .|..|||||||:|||.||...|.::||.|||.||:.:|:||:..:.:|..:.|..| .|...:::
  Rat   127 FLKPWLGDGLLLSTGDKWSRHRHMLTPAFHFNILKPYVKIFNDSTNIMHAKWQRLASQGSARLDM 191

  Fly   169 FPVICLTALDIIAETAMGTKINAQKNPNLPYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQPTEA 233
            |..|.|..||.:.:.......|.|:.|: .|:.|:.:::.::.:|.......||..:.||:  :.
  Rat   192 FEHISLMTLDSLQKCVFSFDSNCQEKPS-EYITAILELSALVARRHQSLLLYVDLFYHLTR--DG 253

  Fly   234 KRQDKAIKVMHDFTENIIRERRETLVNNSKETTPEEEVNFLGQKRRMALLDVLLQSTID-GAPLS 297
            .|..||.:::||||:.:|||||.||.:..    .::.:....:.:.:..:||||.|..: |..||
  Rat   254 MRFRKACRLVHDFTDAVIRERRRTLPDQG----GDDALKAKAKAKTLDFIDVLLLSKDEHGEALS 314

  Fly   298 DEDIREEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELK 362
            |||||.|.|||||.|||||.|.:|:.||.:::|||.|:|.:||:|::|.:.....:...||.:|.
  Rat   315 DEDIRAEADTFMFGGHDTTASGLSWILYNLAKHPEYQERCRQEVRELLRDREPEEIEWDDLAQLP 379

  Fly   363 FMENVIKESLRLHPPVPMIGRWFAEDVEI-RGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPER 426
            |:...||||||||||...|.|...:|:.: .|:.||.|....:.||....:|..:..|:.:.|.|
  Rat   380 FLTMCIKESLRLHPPATAISRCCTQDIMLPDGRVIPKGVICRISIFGTHHNPAVWPDPEVYNPFR 444

  Fly   427 FDADVPQ-IHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLPLGPEPRHSMNIVLRSA 490
            ||||..: ..|.|:|||||||||||||.|||.|||..::..|..|.:||...|||....::||:.
  Rat   445 FDADNGEGRSPLAFIPFSAGPRNCIGQTFAMSEMKVALALTLLRFRVLPDDKEPRRKPELILRAE 509

  Fly   491 NGVHLGLKP 499
            .|:.|.::|
  Rat   510 GGLWLRVEP 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	166/448 (37%)
Cyp4f18	NP_001028858.2	CYP4F	74..515	CDD:410772	167/460 (36%)