Protein Alignment Cyp4d2 and Cyp4a12a

DIOPT Version :9

• Sequence 1: NP_001284806.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_803125.2
• Gene: Cyp4a12a / 277753
• MGIID: 88612
• Length: 508
• Species: Mus musculus
• Alignment Length: 505
• Identity: 172/505 - (34%)
• Similarity: 272/505 - (53%)
• Gaps: 40/505 - (7%)

  Fly     8 LLLVAFATLLLW-DFLWRRRGNGILPGPRPLPFLGNLLMYRGLDPEQIMDFVKK-----NQRKYG 66
            |||:.|.|..|: ...|........|.| |..:|....:.:..|.:.|:..:|.     .|..:|
Mouse    27 LLLLLFKTAQLYLHRQWLLSSTQQFPSP-PSHWLFGHKILKDQDLQDILTRIKNFPSACPQWLWG 90

  Fly    67 RLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLYKLLNCWLGDGLLMSTGRKWHGRRKIITP 131
            ...|:.:.        ||..::.:| .:.....|..|:.|..|:|.||||..|:.|...|:::||
Mouse    91 SKVRIQVY--------DPDYMKLIL-GRSDPKANGSYRFLAPWIGRGLLMLDGQTWFQHRRMLTP 146

  Fly   132 TFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIAETAMGTKINAQKNPN 196
            .||:.||:.:.||......||:::.:......:.:.||..|.|..||.|.:.|...:.:.|.:..
Mouse   147 AFHYDILKPYTEIMADSVRVMLDKWEQIVGQDSTLEIFRHITLMTLDTIMKCAFSHEGSVQLDRK 211

  Fly   197 L-PYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQPTEAKRQDKAIKVMHDFTENIIRERRETLVN 260
            . .|:|||.|:.:::..|..:.:.:.|.|:|::  :...:.:.|.|:.||.|:.:|:.||..|.:
Mouse   212 YKSYIQAVEDLNDLVFSRVRNIFHQNDIIYRVS--SNGCKANSACKLAHDHTDQVIKSRRIQLQD 274

  Fly   261 NSKETTPEEEVNFLGQKRRMALLDVLLQSTID-GAPLSDEDIREEVDTFMFEGHDTTTSAISFCL 324
                   |||:..|.:|||:..||:||.:.:: |..|||:|:|.|||||||||||||.|.||:..
Mouse   275 -------EEELEKLKKKRRLDFLDILLFARMENGKSLSDKDLRAEVDTFMFEGHDTTASGISWIF 332

  Fly   325 YEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESLRLHPPVPMIGRWFAEDV 389
            |.::.:||.|||.::||:.:||:.  :.:|..||.::.:....|||:||::||||.:.|..:..|
Mouse   333 YALATNPEHQQRCRKEIQSLLGDG--TSITWNDLDKMPYTTMCIKEALRIYPPVPSVSRELSSPV 395

  Fly   390 EI-RGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERFDADVPQIHPYAYIPFSAGPRNCIGQK 453
            .. .|:.:|.|.:..:..:.|..:|..:.:|:.|.|.|| |.....|.::::|||.|.|||||::
Mouse   396 TFPDGRSLPKGIHVMLSFYGLHHNPTVWPNPEVFDPSRF-APGSSRHSHSFLPFSGGARNCIGKQ 459

  Fly   454 FAMLEMKSTVSKLLRHFELLPLG-----PEPRHSMNIVLRSANGVHLGLK 498
            |||.|:|..|:..|..|||||..     |.||    |||:|.||:||.||
Mouse   460 FAMNELKVAVALTLLRFELLPDPTRVPIPIPR----IVLKSKNGIHLHLK 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_001284806.1	p450	32..495	CDD:278495	161/475 (34%)
Cyp4a12a	NP_803125.2	p450	52..502	CDD:278495	161/475 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845031
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.650