Protein Alignment Cyp4d2 and Cyp4v3

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001129072.1
• Gene: Cyp4v3 / 266761
• RGDID: 708530
• Length: 525
• Species: Rattus norvegicus
• Alignment Length: 542
• Identity: 214/542 - (39%)
• Similarity: 316/542 - (58%)
• Gaps: 70/542 - (12%)

  Fly     2 LGVVGVLLL---------VAFATLLLWDFL-----WRRRGNGILPGP---RPLPFLGNLLMYRGL 49
            ||:.|..||         ||.||:|| :.|     :.|:...:.|.|   |..|.:|:.|..:..
  Rat     6 LGLSGQKLLLWGAASAVSVAGATVLL-NILQMLVSYARKWQQMRPIPSVARAYPLVGHALFMKPN 69

  Fly    50 DPE---QIMDFVKKNQRKYGRLYRVWI--LHQLAVFSTDPRDIEFVLSSQQHITKNNLYKLLNCW 109
            :.|   ||:.:.:  :.::..:.::||  :..:|::..:  ::|.:|:|.:.|.|:.:||.|..|
  Rat    70 NTEFFQQIIQYTE--EFRHLPIIKLWIGPVPLVALYKAE--NVEVILTSSKQIDKSFMYKFLQPW 130

  Fly   110 LGDGLLMSTGRKWHGRRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICL 174
            ||.|||.|||.||..|||::||:|||.|||.|:::.::|:.::|.:|:...: ....|.|..|.|
  Rat   131 LGLGLLTSTGSKWRARRKMLTPSFHFTILEDFLDVMNEQANILVNKLEKHVN-QEAFNCFFPITL 194

  Fly   175 TALDIIAETAMGTKINAQKNPNLPYVQAVNDVTNILIKRFIHAWQRVD-W--IFRLTQPTEAKRQ 236
            .|||||.|||||..|.||.|.:..||:.|..:::::.:|....|...| |  :|:     |.:..
  Rat   195 CALDIICETAMGKNIGAQSNGDSEYVRTVYRMSDMIYRRMKMPWFWFDLWYLMFK-----EGRDH 254

  Fly   237 DKAIKVMHDFTENIIRERRETLVNNSKETTPEEEVNFLG--------QKRRMALLDVLLQST-ID 292
            .|.:|.:|.||.|:|.||    ||..|     .|.:.:|        :.:|.|.||:||..| .:
  Rat   255 KKGLKSLHTFTNNVIAER----VNARK-----AEQDCIGAGRGPLPSKTKRKAFLDLLLSVTDEE 310

  Fly   293 GAPLSDEDIREEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRD 357
            |..||.||||||||||||||||||.:||::.||.:..:||||:::.:|:.||.|...: ||||.|
  Rat   311 GNKLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQRKVDKELDDVFGRSHR-PVTLED 374

  Fly   358 LGELKFMENVIKESLRLHPPVPMIGRWFAEDVEIRGKHIPAGTNFTMGIFVLLRDPEYFESPDEF 422
            |.:||:::.||||:||:.|.||:..|..:||.|:.|..|..||...:..:.|.|||.||..|:||
  Rat   375 LKKLKYLDCVIKETLRVFPSVPLFARSLSEDCEVAGYKISKGTEAVIIPYALHRDPRYFPDPEEF 439

  Fly   423 RPERFDADVPQ-IHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHF--------ELLPLGPE 478
            :||||..:..| .|||||:|||||||||||||||::|.|:.::.:||.|        |.|.|..:
  Rat   440 QPERFFPENSQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILACILREFWIESNQKREELGLAGD 504

  Fly   479 PRHSMNIVLRSANGVHLGLKPR 500
                  ::||..||:.:.||.|
  Rat   505 ------LILRPNNGIWIKLKRR 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	189/451 (42%)
Cyp4v3	NP_001129072.1	CYP4V	76..515	CDD:410773	191/464 (41%)