Protein Alignment Cyp4d2 and Cyp4a8

DIOPT Version :9

• Sequence 1: NP_001284806.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: XP_038965258.1
• Gene: Cyp4a8 / 266674
• RGDID: 628846
• Length: 510
• Species: Rattus norvegicus
• Alignment Length: 520
• Identity: 165/520 - (31%)
• Similarity: 272/520 - (52%)
• Gaps: 52/520 - (10%)

  Fly     4 VVGVLLLVAFATLLLWDF---------LWRRRGNGILPGPRPLPFLGNLLMYRGLDPEQIMDFVK 59
            ::|.|.:....|:||..|         .|..|.....|.|....|.|:.|.:  |..::..|.:.
  Rat    15 ILGFLQIATVLTVLLLLFKTAQFYLHRRWLLRATQQFPSPPSHWFFGHKLSF--LVDQEFQDILT 77

  Fly    60 --KN------QRKYGRLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLYKLLNCWLGDGLLM 116
              ||      |..:|...|:.:.        ||..::.:| .:.....::.|:.|..|:|.|||:
  Rat    78 RVKNFPSACPQWLWGSNVRIQVY--------DPDYMKLIL-GRSDPKSHHSYRFLAPWIGYGLLL 133

  Fly   117 STGRKWHGRRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIA 181
            ..|:.|...|:::||.||:..|:.:|.|......:|:::.:......:.:.||..|.|..||.|.
  Rat   134 LNGQTWFQHRRMLTPAFHYDTLKPYVGIMADSVRIMLDKWEQIVGQDSTLEIFQHITLMTLDTIM 198

  Fly   182 ETAMGTKINAQKNPNL-PYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQPTEAKRQDKAIKVMHD 245
            :.|...:.:.|.:... .|::||.|:.|:...|..:.:.:.|.|:.|:  :..::...|.::.|:
  Rat   199 KCAFSQEGSVQLDRKYKSYIKAVEDLNNLSFFRIRNIFHQNDIIYSLS--SNGRKARSAWQLAHE 261

  Fly   246 FTENIIRERRETLVNNSKETTPEEEVNFLGQKRRMALLDVLLQSTID-GAPLSDEDIREEVDTFM 309
            .|:.:|:.|:..|.:       |||:..:.||||:..||:||.:.|: |:.|||:|:|.||||||
  Rat   262 HTDQVIKSRKAQLQD-------EEELQKVKQKRRLDFLDILLFARIENGSSLSDKDLRAEVDTFM 319

  Fly   310 FEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESLRL 374
            |||||||.|.||:..|.::.:||.||..::||:.:||:.  :.:|..||.::.:....|||:||:
  Rat   320 FEGHDTTASGISWIFYALATNPEHQQGCRKEIQSLLGDG--ASITWDDLDKMPYTTMCIKEALRI 382

  Fly   375 HPPVPMIGRWFAEDVEI-RGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERFDADVPQIHPYA 438
            :|||..:.|..:..|.. .|:.:|.|....:..:.|..:|..:.:|:.|.|.|| |.....|.::
  Rat   383 YPPVTAVSRMLSTPVTFPDGRSLPKGITVMLSFYGLHHNPTVWPNPEVFDPYRF-APESSRHSHS 446

  Fly   439 YIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLPLG-----PEPRHSMNIVLRSANGVHLGLK 498
            ::|||.|.|||||::|||.|:|..|:..|..|||||..     |.||    :||:|.||::|.||
  Rat   447 FLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPIPIPR----LVLKSKNGIYLRLK 507

  Fly   499  498
              Rat   508  507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_001284806.1	p450	32..495	CDD:278495	154/478 (32%)
Cyp4a8	XP_038965258.1	CYP4B-like	72..505	CDD:410771	148/457 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348484
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.650