Protein Alignment Cyp4d2 and Cyp51

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_037073.1
• Gene: Cyp51 / 25427
• RGDID: 2481
• Length: 503
• Species: Rattus norvegicus
• Alignment Length: 484
• Identity: 123/484 - (25%)
• Similarity: 219/484 - (45%)
• Gaps: 63/484 - (13%)

  Fly     9 LLVAFATLLLWDFLWRRRGNGILPGP----------RPLPFLGNLLMYRGLDPEQIMDFVKKNQR 63
            ||:|.|..|...:|:|.....::..|          .|:||||:.:.: |..|   ::|::....
  Rat    30 LLIACAFTLSLVYLFRLAVGHMVQLPAGAKSPPYIYSPIPFLGHAIAF-GKSP---IEFLENAYE 90

  Fly    64 KYGRLYRVWILHQLAVF--STDPRDIEFVLSSQQHITKNNLY-KLLNCWLGDGLLMST-GRKWHG 124
            |||.::...::.:...:  .:|...:.| .|..:.:....:| :|.....|.|:.... ...:..
  Rat    91 KYGPVFSFTMVGKTFTYLLGSDAAALLF-NSKNEDLNAEEVYGRLTTPVFGKGVAYDVPNAVFLE 154

  Fly   125 RRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIF----PVICLTALDIIAETAM 185
            ::||:....:....:|:|.|.::::.   |..:|..:. ...|:|    .:|.|||    :....
  Rat   155 QKKILKSGLNIAHFKQYVSIIEKEAK---EYFKSWGES-GERNVFEALSELIILTA----SHCLH 211

  Fly   186 GTKINAQKNPNLPYVQAVNDVTNILIKRFIH-AWQRVDWIFRLTQPTEAKRQDKAIKVMHDFTEN 249
            |.:|.:|.|..:..:.|..|      ..|.| ||....|   |..|: .:|:|:|.:.:.:....
  Rat   212 GKEIRSQLNEKVAQLYADLD------GGFSHAAWLLPGW---LPLPS-FRRRDRAHREIKNIFYK 266

  Fly   250 IIRERRETLVNNSKETTPEEEVNFLGQKRRMALLDVLLQSTI-DGAPLSDEDIREEVDTFMFEGH 313
            .|::||     .|||  |.|::           |..||.||. ||.||:|::|...:...:..|.
  Rat   267 AIQKRR-----LSKE--PAEDI-----------LQTLLDSTYKDGRPLTDDEIAGMLIGLLLAGQ 313

  Fly   314 DTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESLRLHPPV 378
            .|:::..::..:.::|...:|.:...|.:.|.||| ..|:|...|.:|..::..|||:|||.||:
  Rat   314 HTSSTTSAWMGFFLARDKPLQDKCYLEQKTVCGED-LPPLTYEQLKDLNLLDRCIKETLRLRPPI 377

  Fly   379 PMIGRWFAEDVEIRGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERFDADVPQI-HPYAYIPF 442
            ..:.|.......:.|..||.|....:...|..|..:.:....:|.|:|:..|.|.. ..:||:||
  Rat   378 MTMMRMAKTPQTVAGYTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPF 442

  Fly   443 SAGPRNCIGQKFAMLEMKSTVSKLLRHFE 471
            .||...|||:.||.:::|:..|.:||.:|
  Rat   443 GAGRHRCIGENFAYVQIKTIWSTMLRLYE 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	105/417 (25%)
Cyp51	NP_037073.1	CYP51-like	88..499	CDD:410668	107/422 (25%)