Protein Alignment Cyp4d2 and erg11

DIOPT Version :9

• Sequence 1: NP_001284806.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_592990.1
• Gene: erg11 / 2542599
• PomBaseID: SPAC13A11.02c
• Length: 495
• Species: Schizosaccharomyces pombe
• Alignment Length: 555
• Identity: 124/555 - (22%)
• Similarity: 217/555 - (39%)
• Gaps: 154/555 - (27%)

  Fly     4 VVGVLLLVAFATLLLW------DFLWRRRGNGILPGPRP------LPFLGNLLMYRGLDPEQIMD 56
            :|.:||.:|.|    |      :.|..|...      ||      :||:|:.:.| |:||   ..
pombe     5 LVSILLSIALA----WYVGYIINQLTSRNSK------RPPIVFHWIPFVGSAVAY-GMDP---YV 55

  Fly    57 FVKKNQRKYGRLYR-VWILHQLAVF-STDPRDIEF-----VLSSQQ---HIT-----KNNLYKLL 106
            |.::.:.|||.::. |.:..::..| .....|..|     .|::::   |:|     |:.:|.:.
pombe    56 FFRECRAKYGDVFTFVCMGRKMTAFLGVQGNDFLFNGKLADLNAEEAYSHLTTPVFGKDVVYDIP 120

  Fly   107 NCWLGDGLLMSTGRKWHGRRKIITPTFHFKILEQFVE-IFDQQSAVMVEQLQSRADGMTP----- 165
            |            ..:...:|.|.....|.....:|. |.::..|.:     |.:....|
pombe   121 N------------HVFMEHKKFIKSGLGFSQFRSYVPLILNEMDAFL-----STSPDFGPGKEGV 168

  Fly   166 ---INIFPVICL-TALDIIAETAMGTKINAQKNPNLPYVQAVNDVTNILIKRFIHAWQRVDWIFR 226
               :...||:.: ||    :.|..|.::  :|..:..:....:|:.        ..:..|:::|.
pombe   169 ADLLKTMPVMTIYTA----SRTLQGAEV--RKGFDAGFADLYHDLD--------QGFSPVNFVFP 219

  Fly   227 LTQPTEAKRQDKAIKVMHDFTENIIRERRETLVNNSKETTPEEEV--NFLGQKRRMALLDVLLQS 289
            .......:|:|:|.|:|......||::||.:..|      |..::  ..:..|.|
pombe   220 WLPLPRNRRRDRAHKIMQKTYLKIIKDRRSSTEN------PGTDMIWTLMSCKYR---------- 268

  Fly   290 TIDGAPLSDEDIREEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVT 354
              ||.||.:.:|...:...:..|..|:.:.|.:.|..:...||:.:.|.:|.:.|:||:.
pombe   269 --DGRPLKEHEIAGMMIALLMAGQHTSAATIVWVLALLGSKPEIIEMLWEEQKRVVGENL----- 326

  Fly   355 LRDLGELKF--------MENVIKESLRLHPPVPMIGRWFAEDVEIRGKH--IPAGTNFTMGIFVL 409
                 ||||        :..||:|:||||||:....|....|:.:.|..  |||.........:.
pombe   327 -----ELKFDQYKDMPLLNYVIQETLRLHPPIHSHMRKVKRDLPVPGSKIVIPANNYLLAAPGLT 386

  Fly   410 LRDPEYFESPDEFRPERF------DADVPQI-HPYA---------YIPFSAGPRNCIGQKFAMLE 458
            ..:.|||....:|.|:|:      |.:..|| :.|.         |:||.||...|||::||.:.
pombe   387 ATEEEYFTHATDFDPKRWNDRVNEDENAEQIDYGYGLVTKGAASPYLPFGAGRHRCIGEQFAYMH 451

  Fly   459 MKSTVSKLLRHFE----------------LLPLGP 477
            :.:.:||.:..:.                .|||||
pombe   452 LSTIISKFVHDYTWTLIGKVPNVDYSSMVALPLGP 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_001284806.1	p450	32..495	CDD:278495	116/521 (22%)
erg11	NP_592990.1	CypX	28..495	CDD:225035	117/528 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	101	1.000	Domainoid score	I1781
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	102	1.000	Inparanoid score	I1639
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.960