Protein Alignment Cyp4d2 and erg11

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_592990.1
• Gene: erg11 / 2542599
• PomBaseID: SPAC13A11.02C
• Length: 495
• Species: Schizosaccharomyces pombe
• Alignment Length: 555
• Identity: 124/555 - (22%)
• Similarity: 217/555 - (39%)
• Gaps: 154/555 - (27%)

  Fly     4 VVGVLLLVAFATLLLW------DFLWRRRGNGILPGPRP------LPFLGNLLMYRGLDPEQIMD 56
            :|.:||.:|.|    |      :.|..|...      ||      :||:|:.:.| |:||   ..
pombe     5 LVSILLSIALA----WYVGYIINQLTSRNSK------RPPIVFHWIPFVGSAVAY-GMDP---YV 55

  Fly    57 FVKKNQRKYGRLYR-VWILHQLAVF-STDPRDIEF-----VLSSQQ---HIT-----KNNLYKLL 106
            |.::.:.|||.::. |.:..::..| .....|..|     .|::::   |:|     |:.:|.:.
pombe    56 FFRECRAKYGDVFTFVCMGRKMTAFLGVQGNDFLFNGKLADLNAEEAYSHLTTPVFGKDVVYDIP 120

  Fly   107 NCWLGDGLLMSTGRKWHGRRKIITPTFHFKILEQFVE-IFDQQSAVMVEQLQSRADGMTP----- 165
            |            ..:...:|.|.....|.....:|. |.::..|.:     |.:....|
pombe   121 N------------HVFMEHKKFIKSGLGFSQFRSYVPLILNEMDAFL-----STSPDFGPGKEGV 168

  Fly   166 ---INIFPVICL-TALDIIAETAMGTKINAQKNPNLPYVQAVNDVTNILIKRFIHAWQRVDWIFR 226
               :...||:.: ||    :.|..|.::  :|..:..:....:|:.        ..:..|:::|.
pombe   169 ADLLKTMPVMTIYTA----SRTLQGAEV--RKGFDAGFADLYHDLD--------QGFSPVNFVFP 219

  Fly   227 LTQPTEAKRQDKAIKVMHDFTENIIRERRETLVNNSKETTPEEEV--NFLGQKRRMALLDVLLQS 289
            .......:|:|:|.|:|......||::||.:..|      |..::  ..:..|.|
pombe   220 WLPLPRNRRRDRAHKIMQKTYLKIIKDRRSSTEN------PGTDMIWTLMSCKYR---------- 268

  Fly   290 TIDGAPLSDEDIREEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVT 354
              ||.||.:.:|...:...:..|..|:.:.|.:.|..:...||:.:.|.:|.:.|:||:.
pombe   269 --DGRPLKEHEIAGMMIALLMAGQHTSAATIVWVLALLGSKPEIIEMLWEEQKRVVGENL----- 326

  Fly   355 LRDLGELKF--------MENVIKESLRLHPPVPMIGRWFAEDVEIRGKH--IPAGTNFTMGIFVL 409
                 ||||        :..||:|:||||||:....|....|:.:.|..  |||.........:.
pombe   327 -----ELKFDQYKDMPLLNYVIQETLRLHPPIHSHMRKVKRDLPVPGSKIVIPANNYLLAAPGLT 386

  Fly   410 LRDPEYFESPDEFRPERF------DADVPQI-HPYA---------YIPFSAGPRNCIGQKFAMLE 458
            ..:.|||....:|.|:|:      |.:..|| :.|.         |:||.||...|||::||.:.
pombe   387 ATEEEYFTHATDFDPKRWNDRVNEDENAEQIDYGYGLVTKGAASPYLPFGAGRHRCIGEQFAYMH 451

  Fly   459 MKSTVSKLLRHFE----------------LLPLGP 477
            :.:.:||.:..:.                .|||||
pombe   452 LSTIISKFVHDYTWTLIGKVPNVDYSSMVALPLGP 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	104/481 (22%)
erg11	NP_592990.1	CYP51-like	60..492	CDD:410668	106/486 (22%)