Protein Alignment Cyp4d2 and Cyp3a18

DIOPT Version :9

• Sequence 1: NP_001284806.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_665725.2
• Gene: Cyp3a18 / 252931
• RGDID: 628709
• Length: 497
• Species: Rattus norvegicus
• Alignment Length: 500
• Identity: 140/500 - (28%)
• Similarity: 244/500 - (48%)
• Gaps: 81/500 - (16%)

  Fly    11 VAFATLLLWDFLWRRRGNGI-----LPGPRPLPFLGNLLMYRGLDPEQIMDFVKKNQRKYGRLYR 70
            |..||.|:..:::....:|:     :|||:|:|..|.:..|    .:.:..|.....:|||   :
  Rat    13 VLLATSLMLFYIYGTYSHGLFKKLGIPGPKPVPLFGTIFNY----GDGMWKFDDDCYKKYG---K 70

  Fly    71 VWILHQ-----LAVFSTDPRDIEFVLSSQQHITKNNLYKLLNC-----WLGDGLLMSTGRKWHGR 125
            :|..::     ||:.  ||..|:.||..:.:    :::....|     ::...:.||...:|...
  Rat    71 IWGFYEGPQPFLAIM--DPEIIKMVLVKECY----SVFTNRRCFGPMGFMKKAITMSEDEEWKRL 129

  Fly   126 RKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIAETAMGTKIN 190
            |.|::|||....|::...:..|....:::.|:.......|||:..:....::|:|..|:.|..::
  Rat   130 RTILSPTFTSGKLKEMFPLMRQYGDTLLKNLRREEAKGEPINMKDIFGAYSMDVITGTSFGVNVD 194

  Fly   191 AQKNPNLPYVQAVNDV----------TNILIKRFIHAWQRVDWIFRLTQPTEAKRQDKAIKVMHD 245
            :..||..|:||....:          .::::..|:..      |:.:...:...||
  Rat   195 SLNNPQDPFVQKAKKILKFQIFDPFLLSVVLFPFLTP------IYEMLNFSIFPRQ--------- 244

  Fly   246 FTENIIRERRETLVNNSKETTPEEEVNFL----------GQKRRMALLDVLLQSTIDGAPLSDED 300
             :.|..::..:|:..|..::..:..|:||          ||:.:.|              |||.:
  Rat   245 -SMNFFKKFVKTMKKNRLDSNQKSRVDFLQLMMNTQNSKGQESQKA--------------LSDLE 294

  Fly   301 IREEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFME 365
            :..:...|:|.|:|.|:::|||.:||::..|.||::||.||...|  ..|:|||...|.|:::::
  Rat   295 MAAQAIIFIFGGYDATSTSISFIMYELATRPNVQKKLQNEIDRAL--PNKAPVTYDALMEMEYLD 357

  Fly   366 NVIKESLRLHPPVPMIGRWFAEDVEIRGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERFDAD 430
            .|:.|||||:|....:.|...:||||.|..||.||..|:.|:.|.|:|||:..|:||.||||..:
  Rat   358 MVVNESLRLYPIATRLDRVSKKDVEINGVFIPKGTVVTIPIYPLHRNPEYWLEPEEFNPERFSKE 422

  Fly   431 -VPQIHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLP 474
             ...|.||.|:||..|||||||.:||::.||..|..:|::|.:.|
  Rat   423 NKGSIDPYVYLPFGNGPRNCIGMRFALISMKLAVIGVLQNFNIQP 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_001284806.1	p450	32..495	CDD:278495	134/473 (28%)
Cyp3a18	NP_665725.2	CYP3A	67..492	CDD:410743	126/441 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810