Protein Alignment Cyp4d2 and Tbxas1

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_036819.1
• Gene: Tbxas1 / 24886
• RGDID: 3826
• Length: 533
• Species: Rattus norvegicus
• Alignment Length: 549
• Identity: 150/549 - (27%)
• Similarity: 246/549 - (44%)
• Gaps: 82/549 - (14%)

  Fly     4 VVGVLLLVAFATLLLW---DFLWRRRGNGILPGPRPLPFLGNLLMYRGLDPEQIMDFVKKNQRKY 65
            ||.|.|.|....||.|   ....|.|..|| ..|.|.||:|||:.:|....|..::.    :.:|
  Rat    15 VVTVTLSVVLLALLKWYSTSAFSRLRKLGI-RHPEPSPFVGNLMFFRQGFWESHLEL----RERY 74

  Fly    66 GRLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLYKLLNCWL-GDGLLMSTGRKWHGRRKII 129
            |.|...::..::.:..:||..|:.||........|.:...|...| .|.:||...|:|...|..:
  Rat    75 GPLCGYYLGRRMYIVISDPDMIKEVLVENFSNFSNRMASGLEPKLIADSVLMLRDRRWEEVRGAL 139

  Fly   130 TPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIAETAMGTKINAQKN 194
            ...|..:.|.:...:..|...:::..|:..|......:|....|....:::|..|.|.::|:|..
  Rat   140 MSAFSPEKLNEMTPLISQACELLLSHLKHSAASGDAFDIQRCYCCFTTNVVASVAFGIEVNSQDA 204

  Fly   195 PNLPYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQPTEA------------------KRQDKAIK 241
            |..|:||              |. ||| :.|...:|..|                  |.:|:
  Rat   205 PEDPFVQ--------------HC-QRV-FAFSTPRPLLALILSFPSIMVPLARILPNKNRDE--- 250

  Fly   242 VMHDFTENIIRERRETLVNNSKETTPEEEVNF----LGQKRRMALLDV--------LLQS----- 289
             ::.|...:|   |..:....|:|..|...:|    |..:|.|:.:.|        .|.|
  Rat   251 -LNGFFNTLI---RNVIALRDKQTAEERRGDFLQMVLDAQRSMSSVGVEAFDMVTEALSSAECMG 311

  Fly   290 --------TIDGAPLSDEDIREEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLG 346
                    |....||:.::|..:...|:..||:.||:.:||..|.::.|||.|:||.:|: |:..
  Rat   312 DPPQRCHPTSTAKPLTVDEIAGQAFLFLIAGHEITTNTLSFITYLLATHPECQERLLKEV-DLFM 375

  Fly   347 EDRKSPVTLRDLGELKFMENVIKESLRLHPPVPMIGRWFAEDVEIRGKHIPAGTNFTMGIFVLLR 411
            |...:|........|.:::.|:.|:||::||.....|..|:|.|:.|:|||||:...:.:..|..
  Rat   376 EKHPAPEYCNLQEGLPYLDMVVAETLRMYPPAFRFTREAAQDCEVLGQHIPAGSVLEIAVGALHH 440

  Fly   412 DPEYFESPDEFRPERFDADVP-QIHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLPL 475
            |||::.:|:.|.||||.|:.. |..|:.|:||.||||:|:|.:..:|.:|.|:.::|..|. ...
  Rat   441 DPEHWPNPETFDPERFTAEARLQQKPFTYLPFGAGPRSCLGVRLGLLVVKLTLLQVLHKFR-FEA 504

  Fly   476 GPEPRHSMNIVLRSA----NGVHLGLKPR 500
            .||.:..:.:..:||    |||::.:..|
  Rat   505 CPETQVPLQLESKSALCPKNGVYVKIVSR 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	127/477 (27%)
Tbxas1	NP_036819.1	cytochrome_P450	74..527	CDD:477761	127/477 (27%)