Protein Alignment Cyp4d2 and Cyp12d1-p

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_610635.4
• Gene: Cyp12d1-p / 246648
• FlyBaseID: FBgn0050489
• Length: 521
• Species: Drosophila melanogaster
• Alignment Length: 497
• Identity: 114/497 - (22%)
• Similarity: 212/497 - (42%)
• Gaps: 106/497 - (21%)

  Fly    31 LPGPRPLPFLGNLLMYRGLDPEQIMDFVKKNQRKYGRLY--------RVWILHQLAVFSTDPRDI 87
            :|.|....|:...:.........|.::....:::||.:|        :.|:    ..|:|  :||
  Fly    45 IPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWV----TTFNT--KDI 103

  Fly    88 EFVLSSQ----------------QHITKNNLYKLLNCWLGD--GLLMSTGRKWHGRRKIITPTF- 133
            |.|..::                :|: :.::|       |:  ||:.|....|...|..|.|.|
  Fly   104 EMVFRNEGIWPRRDGLDSIVYFREHV-RPDVY-------GEVQGLVASQNEAWGKLRSAINPIFM 160

  Fly   134 ---------------HFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIAET 183
                           :.:.:|:..||.|.::..:.|........:    :|..:.|.|.|    .
  Fly   161 QPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRL----VFESLGLVAFD----R 217

  Fly   184 AMG-TKINAQKNPNLPYVQAVNDVTNILIKRFIH--AWQRVDWIFRLTQPTEAKRQDKAIKVMHD 245
            .|| .:.|...:..|...|...|:..:..|..|.  .|:.:      :.||..|.:    :.::|
  Fly   218 QMGLIRKNRDNSDALTLFQTSRDIFRLTFKLDIQPSMWKII------STPTYRKMK----RTLND 272

  Fly   246 ---FTENIIRERRETLVNNSKETTPEEEVNFLGQKRRMALLD--VLLQSTIDGAPLSDEDIREEV 305
               ..:.:::|.::.|   .|.....|::|......|:..:|  |.:..::|
  Fly   273 SLNVAQKMLKENQDAL---EKRRQAGEKINSNSMLERLMEIDPKVAVIMSLD------------- 321

  Fly   306 DTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKE 370
              .:|.|.|.|.:.:|..|..:|:||:.|.:|::|:..:: ..:.|.:...::.::.::..||||
  Fly   322 --ILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIM-PTKDSLLNEENMKDMPYLRAVIKE 383

  Fly   371 SLRLHPPVPMIGRWFAEDVEIRGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERFDADVP--- 432
            :||.:|......|....||.:.|..:|.||...:|..||:::..|:..||||.|||:..|..
  Fly   384 TLRYYPNGLGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGK 448

  Fly   433 --QIHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFEL 472
              |:.|:.::||..|||.|||::...|||::||:||:|:|.:
  Fly   449 KMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHV 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	109/462 (24%)
Cyp12d1-p	NP_610635.4	CYP24A1-like	76..508	CDD:410677	110/466 (24%)