Protein Alignment Cyp4d2 and Cyp4a29

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001093653.1
• Gene: Cyp4a29 / 230639
• MGIID: 3717143
• Length: 509
• Species: Mus musculus
• Alignment Length: 502
• Identity: 164/502 - (32%)
• Similarity: 272/502 - (54%)
• Gaps: 26/502 - (5%)

  Fly     4 VVGVLLLVAFATLLLWDFLWRRRGNGILPGPRPLPFLGNLLMYRGLDPE--QIMDFVKKNQRKYG 66
            ::|:|||:..|........|..|.....|.|......|:.|.:: :|.|  .|:.:::|....:
Mouse    24 LIGLLLLLFKAAQHYLRRQWLLRALYQFPSPPSHWLFGHCLQFK-VDEELRWILRYLEKFPGAF- 86

  Fly    67 RLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLYKLLNCWLGDGLLMSTGRKWHGRRKIITP 131
             |:.:|..| :.:...||..::.:|....  .|.:||:.|..|||.||....|.:|...|:::||
Mouse    87 -LHWIWGSH-VFIKVCDPDYMKVILGRAD--PKASLYRFLTPWLGHGLFFLNGDEWFQHRRLLTP 147

  Fly   132 TFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIAETAMGTKINAQ-KNP 195
            .||:.||:.:|.|......||:|:.:..|.....:.||..|.|..||.|.:.|...:.:.| ...
Mouse   148 AFHYDILKPYVGIMADSVQVMLEKWEQIACQDITLEIFHPISLMMLDTIMKYAFSYQGSVQLDRS 212

  Fly   196 NLPYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQPTEAKRQDKAIKVMHDFTENIIRERRETLVN 260
            :..|:|||:|:.|::..|..:.:...|.|:.||  :.::|.:.|.::.|:.|:.:::.|:..|.:
Mouse   213 SQAYLQAVSDLNNLVTSRMKNVFLHNDIIYNLT--SHSRRTNSACQIAHEHTDRVVKLRKAQLQD 275

  Fly   261 NSKETTPEEEVNFLGQKRRMALLDVLLQSTI-DGAPLSDEDIREEVDTFMFEGHDTTTSAISFCL 324
            |       :.:..|..||.:..||:||.|.: ||:.|||:.:|.|||:.||.||||..|.||:..
Mouse   276 N-------KSMKKLRGKRCLDFLDILLLSRMDDGSSLSDKALRAEVDSLMFGGHDTPASGISWVF 333

  Fly   325 YEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESLRLHPPVPMIGRWFAEDV 389
            |.::.||:.|||.::|::.:||:.  ||:|...|.::.:....|||:|||:||:|.:||..:..|
Mouse   334 YALATHPDHQQRCREEVQSLLGDG--SPITWDHLHQMPYTTMCIKEALRLYPPIPSVGRKLSTPV 396

  Fly   390 EI-RGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERFDADVPQIHPYAYIPFSAGPRNCIGQK 453
            .. .|:.:|.|....:..:.|..:|:.:.:|:.|.|.||..:..| |.:|::|||.|.|||||:.
Mouse   397 TFPDGRSLPKGITVLLHFYALHHNPKVWPNPEVFDPSRFAMNSVQ-HSHAFLPFSGGSRNCIGKH 460

  Fly   454 FAMLEMKSTVSKLLRHFELLPLGPE--PRHSMNIVLRSANGVHLGLK 498
            .||..:|..|:..|..||||| .|.  |..:..:||:|.||::|.|:
Mouse   461 LAMNVLKVAVALTLLRFELLP-DPSRVPIPTQQLVLKSKNGIYLHLR 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	147/433 (34%)
Cyp4a29	NP_001093653.1	CYP4B-like	75..504	CDD:410771	149/446 (33%)