Protein Alignment Cyp4d2 and Tbxas1

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_035669.3
• Gene: Tbxas1 / 21391
• MGIID: 98497
• Length: 533
• Species: Mus musculus
• Alignment Length: 537
• Identity: 145/537 - (27%)
• Similarity: 251/537 - (46%)
• Gaps: 58/537 - (10%)

  Fly     4 VVGVLLLVAFATLLLW---DFLWRRRGNGILPGPRPLPFLGNLLMYR-GLDPEQIMDFVKKNQRK 64
            :|.|.||||...||.|   ....|....|| ..|:|.||:|||:.:| |....|:     :.:.:
Mouse    15 IVTVTLLVALLALLKWYSMSAFSRLEKLGI-RHPKPSPFVGNLMFFRQGFWESQL-----ELRER 73

  Fly    65 YGRLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLYKLLN-CWLGDGLLMSTGRKWHGRRKI 128
            ||.|...::..::.|..::|..|:.||........|.:...|. ..:.|.:|:...|:|...|..
Mouse    74 YGPLCGYYLGRRMHVVISEPDMIKQVLVENFSNFSNRMASGLEPKMVADSVLLLRDRRWEEVRGA 138

  Fly   129 ITPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIAETAMGTKINAQK 193
            :..:|..:.|::...:..|...::|..|:..|......||....|...:|::|..|.||::::|.
Mouse   139 LMSSFSPEKLDEMTPLISQACELLVAHLKRYAASRDAFNIQRCYCCYTIDVVASVAFGTQVDSQN 203

  Fly   194 NPNLPYVQAVNDVTNILIKR----FIHAWQRVDWIFRLTQPTEAKRQDKAIKVMHDFTENII--- 251
            :|..|:||.....:...|.|    .|.::..:  :..|.:....|.:|:.....:....|:|
Mouse   204 SPEDPFVQHCRRASTFCIPRPLLVLILSFPSI--MVPLARILPNKNRDELNGFFNTLIRNVIALR 266

  Fly   252 -----RERRETLVNNSKETTPEEEVNFLGQKRRMALLDVLLQS----------------TIDGAP 295
                 .|||...:....:.  :..:|.:|.:.    .|::.:|                |....|
Mouse   267 DQQAAEERRRDFLQMVLDA--QHSMNSVGVEG----FDMVPESLSSSECTKEPPQRCHPTSTSKP 325

  Fly   296 LSDEDIREEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPV-TLRDLG 359
            .:.::|..:...|:..||:..|:.:||..|.::.||:.|:||.:|:...:|   |.|. ....|.
Mouse   326 FTVDEIVGQAFLFLIAGHEVITNTLSFITYLLATHPDCQERLLKEVDLFMG---KHPAPEYHSLQ 387

  Fly   360 E-LKFMENVIKESLRLHPPVPMIGRWFAEDVEIRGKHIPAGTNFTMGIFVLLRDPEYFESPDEFR 423
            | |.:::.||.|:||::||.....|..|:|.|:.|:.|||||...:.:..|..|||::.:|:.|.
Mouse   388 EGLPYLDMVISETLRMYPPAFRFTREAAQDCEVLGQRIPAGTVLEIAVGALHHDPEHWPNPETFD 452

  Fly   424 PERFDADVP-QIHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLPLGPEPRHSMNIVL 487
            ||||.|:.. |..|:.|:||.||||:|:|.:..:|.:|.|:.::|..|. ....||.:..:.:..
Mouse   453 PERFTAEARLQRRPFTYLPFGAGPRSCLGVRLGLLVVKLTILQVLHKFR-FEASPETQVPLQLES 516

  Fly   488 RSA----NGVHLGLKPR 500
            :||    |||::.:..|
Mouse   517 KSALGPKNGVYIKIVSR 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	121/464 (26%)
Tbxas1	NP_035669.3	cytochrome_P450	74..527	CDD:477761	121/464 (26%)