Protein Alignment Cyp4d2 and cyp-13A2

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_496109.1
• Gene: cyp-13A2 / 188360
• WormBaseID: WBGene00011676
• Length: 515
• Species: Caenorhabditis elegans
• Alignment Length: 551
• Identity: 136/551 - (24%)
• Similarity: 237/551 - (43%)
• Gaps: 95/551 - (17%)

  Fly     5 VGVLLLVAFATLL--------LWDFLWRRRGNGILPGPRPLPFLGNLLMYRGLDPEQIMDFVKKN 61
            :|.:|.|.|:..|        :|.: |.|:|   :.|||..||:|            ::|.:.::
 Worm     3 LGFVLAVTFSIFLGILTYYLWIWTY-WMRKG---VKGPRGRPFVG------------VLDVLLEH 51

  Fly    62 Q-----------RKYGRLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLY-KLLNCWLGD-- 112
            :           :|||::|......|..:...||..:..:...|    .:|.| :.||...|:
 Worm    52 ETPGLIKLGEWTKKYGKVYGYTDGTQRTLVVADPAMVHEIFVKQ----FDNFYGRKLNPIQGNPE 112

  Fly   113 -----GLLMSTGRKWHGRRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVI 172
                 .||.:.|.:|...|.|.:.:|....|::.....:..:..::..::.:..|...|::....
 Worm   113 KEQRVHLLAAQGYRWKRLRTISSQSFSNASLKKMKRTVEDSALELLRHIEKQTAGGEQIDMLRFY 177

  Fly   173 CLTALDIIAETAMG-TKINAQKNPNLPYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQPTEAKRQ 236
            ....:|:|...||| |.....|||          :.|::.:.|..:.:.:..|.::..|.....:
 Worm   178 QEYTMDVIGRFAMGQTDSMMFKNP----------IVNVVREIFCGSRKNLMLICQVFPPIGQFIR 232

  Fly   237 D-----------KAIKVMHDFTENIIRERRETLVNNSKETTPE-----------EEVNFLGQKRR 279
            |           |...:|.|.....|.:|.......|.|  |:           ::|:|..:.|.
 Worm   233 DLTFKFPRIPAFKLYSIMQDVVAARIAQREREKGAESGE--PQDFIDLFLDARSDDVDFSAEARE 295

  Fly   280 MALLDVLLQSTIDGAPLSDEDIREEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDV 344
                |...::......||.:::..:...|:..|.|||..::|:..|.::.:|::|:::.:||...
 Worm   296 ----DFSKRNLKITKELSADEVVGQCFLFLIGGFDTTALSLSYVTYLLAVNPKIQEKVIEEIARE 356

  Fly   345 LGEDRKSPVTLRDLGELKFMENVIKESLRLHPPVPMI-GRWFAEDVEIRGKHIPAGTNFTMGIFV 408
            .|   .|.|....||.||:|:.||||:|||:|...:. .|...:...:.|..|.||....|..:.
 Worm   357 FG---TSEVEFEKLGRLKYMDCVIKEALRLYPLASISNSRKCMKTTTVNGVKIEAGVYVQMDTWS 418

  Fly   409 LLRDPEYF-ESPDEFRPERFDADVPQIHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFEL 472
            |..|||.: |...||:|||:..|.|..|..||:||..|||.|||.:.|::|.|..::.||::: .
 Worm   419 LHYDPELWGEDVKEFKPERWSTDEPLEHKGAYLPFGLGPRQCIGMRLAIMEQKILLTHLLKNY-T 482

  Fly   473 LPLGPEPRHSMNIV---LRSANGVHLGLKPR 500
            ...|.:.|..:.:|   ..|...|.:.|:||
 Worm   483 FETGNKTRIPLKLVGSATTSPEDVFVHLRPR 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	115/464 (25%)
cyp-13A2	NP_496109.1	CYP3A-like	65..508	CDD:410678	117/466 (25%)