Protein Alignment Cyp4d2 and cyp-13A3

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_496110.1
• Gene: cyp-13A3 / 188359
• WormBaseID: WBGene00011675
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 549
• Identity: 150/549 - (27%)
• Similarity: 246/549 - (44%)
• Gaps: 89/549 - (16%)

  Fly     4 VVGVLLLVAFATLLLWDF-LWRRRGNGILPGPRPLPFLGNLLMYRGLDPEQIM---DFVKKNQRK 64
            ::.:.|.:...|..||.: .|.|:|   :.|||.|||.|.:..::..:...|:   |:.|    :
 Worm     6 LIAIALFIGVFTYYLWIWSFWMRKG---IKGPRGLPFFGIINAFQSYEKPWILRLGDWTK----E 63

  Fly    65 YGRLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLY-KLLNCWLGD-------GLLMSTGRK 121
            ||.:|......:..:..:||..:..|...|    .:|.| :..|...||       .|:.|.|.:
 Worm    64 YGPMYGFTDGVEKTLVVSDPEFVHEVFVKQ----FDNFYARKQNPLQGDPDKDPRIHLVTSQGHR 124

  Fly   122 WHGRRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIAETAMG 186
            |...|.:.:|||..|.|.:.....::..|.|:..|:....|...|:|........:|||.:.|||
 Worm   125 WKRLRTLASPTFSNKSLRKIFSTVEESVAEMMRHLEKGTAGGKTIDILEYYQEFTMDIIGKIAMG 189

  Fly   187 TKINAQ-KNPNLPYVQAV-NDVTNIL-----IKRFIHAWQRVDWIFRLTQPTEAKRQDKAIKVMH 244
            ...:.. :||.|..::|: |...||:     |..|..:..|  |.|     ::.........:||
 Worm   190 QSGSMMFENPWLDKIRAIFNTRGNIIFIICGIVPFTGSIFR--WFF-----SKVPTAQTVTSLMH 247

  Fly   245 DFTENIIRERRETLVNNSKETTPEEEVNFLGQKRRMALLDVLLQSTIDGAPLSDE---------- 299
              |..|      .|....::...:|:............:|:.|....|...|.||
 Worm   248 --TLEI------ALTKRVEQRAADEKAGIESSGEPQDFIDLFLDVQADTDFLEDETKNGFARSQI 304

  Fly   300 ----------DIREEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSP-- 352
                      :|..::..|:..|:|||..::|:..|.::||||:|::||:|:      ||:.|
 Worm   305 VKVDKHLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLARHPEIQKKLQEEV------DRECPDP 363

  Fly   353 -VTLRDLGELKFMENVIKESLRLHPPVPMI-GRWFAEDVEIRGKHIPAGTNFTMGIFVLLRDPEY 415
             ||...|.:||:||.||||:|||:|...:: .|...:...:.|..|..|||.....:.|..||::
 Worm   364 EVTFDQLSKLKYMECVIKETLRLYPLASIVHNRKCMKSTTVLGMKIEEGTNVQADTWTLHYDPKF 428

  Fly   416 F-ESPDEFRPERFDA-DVPQIHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFEL------ 472
            : |:.:||:|||::: |...:...||:||..|||.|||.:.|.:|.|..::::|:.:.|
 Worm   429 WGENANEFKPERWESGDEQAVAKGAYLPFGLGPRICIGMRLAYMEEKMLLAQILKKYSLETTFET 493

  Fly   473 -LPLGPEPRHSMNIVLRSANGVHLGLKPR 500
             :||     ..:.|...:...|||.||||
 Worm   494 HIPL-----KLVGIATTAPTNVHLKLKPR 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	126/476 (26%)
cyp-13A3	NP_496110.1	CYP3A-like	63..509	CDD:410678	126/475 (27%)