Protein Alignment Cyp4d2 and cyp-13A8

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_496115.1
• Gene: cyp-13A8 / 188358
• WormBaseID: WBGene00011674
• Length: 509
• Species: Caenorhabditis elegans
• Alignment Length: 567
• Identity: 136/567 - (23%)
• Similarity: 235/567 - (41%)
• Gaps: 137/567 - (24%)

  Fly     8 LLLVAFATLLLWDF-LWRRRGNGILPGPRPLPFLG--NLLMYRGLDPEQIMDFVKKNQRKYGRLY 69
            |:|::..|...|.: .|:|||   ||||..:|..|  ..::.....|...:   :|..::||::|
 Worm     5 LILISIVTYYFWHWTFWKRRG---LPGPWGVPIFGKAGAMLEDSFPPGYTL---QKWTKEYGKIY 63

  Fly    70 RVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLY-KLLNCWLGD-------GLLMSTGRKWHGRR 126
            ......|..:..:||..::.:|..|.    :|.| :..|...||       .::.:.|.:|...|
 Worm    64 GFTEGMQKVMVISDPDLVQEILVKQY----DNFYGRKHNPVQGDPDKDKDIHIVGAQGFRWKRLR 124

  Fly   127 KIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIAETAMGTKINA 191
            .|..|.|....:::.:...:..:..::::|:..::....:|:.........|:|:..|||...:.
 Worm   125 TITAPAFSNGSIKKVLTTMEDSTQELMKKLREESENGKAVNMHLFYQEYTFDVISRVAMGQPDSQ 189

  Fly   192 Q-KNPNLPYVQAVNDVTNILIKRFIH-AWQ-------------RVDWIF---------------- 225
            . |||.|..|:..          |.| .||             .:.|:|
 Worm   190 MFKNPLLKDVKGF----------FEHNRWQIWMFSGGFPFAVSFLKWLFIKVGKFGAGPFIVVQK 244

  Fly   226 --------RLTQPTEAKRQDKAIKVMHDFTENIIRERRETLVNNSKETTPEEEVNFLGQKRRMAL 282
                    |:.|....|:.........|:.:..:..|.|  |.:..|:..|...:
 Worm   245 SVTDAVMSRIAQREADKKHGVEPGEAADYIDMFLNARAE--VEHFGESNDEFHKS---------- 297

  Fly   283 LDVLLQSTIDGAPLSDEDIREEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGE 347
                  |:.:...|:.::|..:...|:..|.|||..::|:..|.::.:|::|.:||.|:
 Worm   298 ------SSYNNRQLTTQEIISQCFVFLVAGFDTTAISLSYVTYFLALNPKIQSKLQDEV------ 350

  Fly   348 DRKSP---VTLRDLGELKFMENVIKESLRLHPPVPMIGRWFAEDVEIR--------GKHI-PAGT 400
            |::.|   :|...|.:||:|:|||||||||.|        ||.....|        |:.| .||.
 Worm   351 DKECPNDEITFDQLSKLKYMDNVIKESLRLFP--------FASFANSRRCMRNTVIGEQIVEAGV 407

  Fly   401 NFTMGIFVLLRDPEYF-ESPDEFRPERFDADV-PQIHPYAYIPFSAGPRNCIGQKFAMLEMKSTV 463
            :..:..:.|..|...: ...:||:|||:|:.: ||   .||:.|.||||.|:|.:||:||.|..:
 Worm   408 DVMIDTWTLHHDKNVWGNDVEEFKPERWDSPLTPQ---QAYLSFGAGPRVCLGMRFALLEQKGLL 469

  Fly   464 SKLLRHFEL-------LPLGPEPRHSMNIVLRSA---NGVHLGLKPR 500
            |.:|:.:..       ||:        .:|.|:.   ..:.|.||||
 Worm   470 SHILKKYTFETNAKTQLPI--------KLVGRATARPENLFLSLKPR 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	114/499 (23%)
cyp-13A8	NP_496115.1	CYP3A-like	58..500	CDD:410678	115/498 (23%)