Protein Alignment Cyp4d2 and cyp-13A5

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_496112.1
• Gene: cyp-13A5 / 188356
• WormBaseID: WBGene00011672
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 554
• Identity: 143/554 - (25%)
• Similarity: 243/554 - (43%)
• Gaps: 119/554 - (21%)

  Fly     9 LLVAFATLL--------LWDFLWRRRGNGILPGPRPLPFLGNLLMYRGLDPEQIMDFVKKNQRKY 65
            :|:|.|:.:        :|.| |.|:|   :.|||..||.|.:..::..:...::. :.:..::|
 Worm     5 ILIAGASFIGLLTYYIWIWSF-WIRKG---VKGPRGFPFFGVIHEFQDYENPGLLK-LGEWTKEY 64

  Fly    66 GRLYRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLY-KLLNCWLGD-------GLLMSTGRKW 122
            |.:|.:....:..:..::|..:..|...|    .:|.| :..|...||       .|:.:.|.:|
 Worm    65 GPIYGITEGVEKTLIVSNPEFVHEVFVKQ----FDNFYGRKTNPIQGDPNKNKRAHLVSAQGHRW 125

  Fly   123 HGRRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIAETAMG- 186
            ...|.:.:|||..|.|.:.:...::....::..|...:.....:::........||||...|||
 Worm   126 KRLRTLSSPTFSNKNLRKIMSTVEETVVELMRHLDDASAKGKAVDLLDYYQEFTLDIIGRIAMGQ 190

  Fly   187 TKINAQKNPNLPYVQA-----------VNDVTNILIKRFIHAWQRVDWIFRLTQPTEAKRQDKAI 240
            |:....:||.||.|:.           |:.:..|....|...:.|    |...||        |.
 Worm   191 TESLMFRNPMLPKVKGIFKDGRKLPFLVSGIFPIAGTMFREFFMR----FPSIQP--------AF 243

  Fly   241 KVMHDFTENIIRERRETLVNNSK---ETTPE------------------EEVNFLG-QKRRMALL 283
            .:| ...|..:.:|.|....:.|   |.:.|                  ||.:.|| .|..:|.:
 Worm   244 DIM-STVEKALNKRLEQRAADEKAGIEPSGEPQDFIDLFLDARANVDFFEEESALGFAKTEIAKV 307

  Fly   284 DVLLQSTIDGAPLSDEDIREEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGED 348
            |  .|.|.|       :|..::..|:..|:|||..::|:..|.::||||:|::||:|:      |
 Worm   308 D--KQLTFD-------EIIGQLFVFLLAGYDTTALSLSYSSYLLARHPEIQKKLQEEV------D 357

  Fly   349 RKSP---VTLRDLGELKFMENVIKESLRLHPPVPMI-GRWFAEDVEIRGKHIPAGTNFTMGIFVL 409
            |:.|   ||...:.:||:||.|:||:||::|...:: .|...::..:.|..|..|||..:..:.|
 Worm   358 RECPNPEVTFDQISKLKYMECVVKEALRMYPLASIVHNRKCMKETNVLGVQIEKGTNVQVDTWTL 422

  Fly   410 LRDPEYF-ESPDEFRPERFDADVPQIHPYA---YIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHF 470
            ..||:.: |..:||||||:::.....  ||   |:||..|||.|||.:.||:|.|..::.:|:.:
 Worm   423 HYDPKVWGEDANEFRPERWESGDELF--YAKGGYLPFGMGPRICIGMRLAMMEKKMLLTHILKKY 485

  Fly   471 EL-------LPL--------GPE-------PRHS 482
            ..       :||        .|.       ||||
 Worm   486 TFETSTQTEIPLKLVGSATTAPRSVMLKLTPRHS 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	128/489 (26%)
cyp-13A5	NP_496112.1	CYP3A-like	63..511	CDD:410678	125/481 (26%)