Protein Alignment Cyp4d2 and cyp-13B2

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_510369.2
• Gene: cyp-13B2 / 187068
• WormBaseID: WBGene00010606
• Length: 511
• Species: Caenorhabditis elegans
• Alignment Length: 522
• Identity: 125/522 - (23%)
• Similarity: 229/522 - (43%)
• Gaps: 73/522 - (13%)

  Fly     1 MLGVVGVLLLVAFATLLLW-DFLWRRRGNGILPGPRPLPFLGNLLMYRGLDPEQIMDF-VKKNQR 63
            ::.::||:     |....| ...|:|||   :.||..|||:|:  .|...|.|:...| :.|..:
 Worm     7 LVAIIGVV-----AGYFKWIHSYWKRRG---IEGPVGLPFIGS--FYDLADREKPRGFIINKWTK 61

  Fly    64 KYGRLYRVW--ILHQLAVFSTDPRDIEFVLSSQ---QHITKNNLYKLLNCWLGD---GLLMSTGR 120
            .:|:::..:  ::..|.|...|.....|:....   ...|.|.::..|.|...:   .|..:.|.
 Worm    62 MFGKVFGYYEGVIPVLVVSDLDMLQEMFIKKFDCFYARKTTNLIHGNLECSQEEPRVNLFAARGA 126

  Fly   121 KWHGRRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIAETAM 185
            :|...|.:.:|.|..|.|:|..|..:.....||:.:..:.:| ...||.........|:|:..||
 Worm   127 RWKRLRALASPAFSVKALKQIHETMEDSVFSMVDHMSKQVNG-EAFNIHEYYQEFTYDVISRLAM 190

  Fly   186 GTKINAQKNPNLPYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQP------------TEAKRQDK 238
            |...:.|.|         |:..:|:.|.|:...:...|...:..|            .||.|...
 Worm   191 GQTYSEQFN---------NEGVDIVKKIFLRKNRVYPWYLAVMFPGFENTIKNTFFNHEAVRGGD 246

  Fly   239 AIKVMHDFTENIIRERRETLVNNSKETTPEEEVNFLGQKRRMALLDVLLQSTI-DGA-------P 295
            ..|:: .|.|..:.:|.:...:|.::.......:|:..     .||....:.| |.|       .
 Worm   247 VGKLL-KFCETAVHDRLKERADNVEQGIENPHNDFIDM-----FLDYYTDTNIEDNAFGIKVEKK 305

  Fly   296 LSDEDIREEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGE 360
            ::.||:......|:..|.|||.:.:::..|.:::||:..:::|.||..:...:.   ::..|:|:
 Worm   306 VTSEDVIGACFVFLLAGFDTTANTLAYASYLLAKHPQEMRKVQDEIDRICTSEH---ISYDDIGK 367

  Fly   361 LKFMENVIKESLRLHPPVPMIGRWFA------EDVEIRGKHIPAGTNFTMGIFVLLRDPEYF-ES 418
            |::|:.||:|:||::|..     |||      :...:...:|..|......:..|....|.: ::
 Worm   368 LRYMDAVIREALRMYPVA-----WFACSRECVQATTLGNYYIEKGVRIEADVRALHYSEEIWGKN 427

  Fly   419 PDEFRPERFDADVPQIHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFELLPLGPEPRHSM 483
            .:||.|||:....|: |..::|||.||||.|:|.:..:.|.|:.::.|||.|.:| .||:....:
 Worm   428 ANEFVPERWLESSPR-HNMSWIPFGAGPRQCVGMRLGLSEAKTALAHLLRRFSIL-AGPKTEKEL 490

  Fly   484 NI 485
            ::
 Worm   491 HL 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	106/455 (23%)
cyp-13B2	NP_510369.2	CYP3A-like	62..505	CDD:410678	106/457 (23%)