DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d2 and cyp-31A5

DIOPT Version :9

Sequence 1:	NP_001284806.1	Gene:	Cyp4d2 / 31192	FlyBaseID:	FBgn0011576	Length:	501	Species:	Drosophila melanogaster
Sequence 2:	NP_001343697.1	Gene:	cyp-31A5 / 13198891	WormBaseID:	WBGene00013381	Length:	308	Species:	Caenorhabditis elegans

Alignment Length:	264	Identity:	89/264 - (33%)
Similarity:	145/264 - (54%)	Gaps:	12/264 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LGVVGVLLLVAFATLLLWDFLWRRRGNGILP---GPRPLPFLGNLLMYRGLDPEQIMDFVKKNQR 63
            :||:...:|:|.||::.|......|...:|.   .||..|.:|:.|:.:. |||..|:.|.....
Worm     1 MGVIIPAVLLASATVIAWLIYKHLRMRQVLKHLNQPRSYPIVGHGLITKP-DPEGFMNQVIGMGY 64

  Fly    64 KY--GRLYRVWI--LHQLAVFSTDPRDIEFVLSSQQHITKNNLYKLLNCWLGDGLLMSTGRKWHG 124
            .|  .|:..:||  ...|.::|.|.  :|.:.||.:|:.|...|.||..|||..:|.|...:|..
Worm    65 LYPDPRMCLLWIGPFPCLMLYSADL--VEPIFSSTKHLNKGFAYVLLEPWLGISILTSQKEQWRP 127

  Fly   125 RRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIAETAMGTKI 189
            :||::|||||:.||:.|:.||::||.:::::|.........:::..||.|..||||.||:||..|
Worm   128 KRKLLTPTFHYDILKDFLPIFNEQSKILIQKLCCLGVADEEVDVLSVITLCTLDIICETSMGKAI 192

  Fly   190 NAQKNPNLPYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQPTEAKRQDKAIKVMHDFTENIIRER 254
            .||...|..||.||:.:..::.||..:......:|:.||:  :.:..:|.:.::||||:.:|.||
Worm   193 GAQLAENNEYVWAVHTINKLISKRTNNPLMWNSFIYNLTE--DGRTHEKCLHILHDFTKKVIVER 255

  Fly   255 RETL 258
            :|.|
Worm   256 KEAL 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_001284806.1	p450	32..495	CDD:278495	80/234 (34%)
cyp-31A5	NP_001343697.1	p450	36..>261	CDD:325183	80/229 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163518
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.750