Protein Alignment Cyp4d2 and Cyp51

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_064394.2
• Gene: Cyp51 / 13121
• MGIID: 106040
• Length: 503
• Species: Mus musculus
• Alignment Length: 484
• Identity: 124/484 - (25%)
• Similarity: 220/484 - (45%)
• Gaps: 63/484 - (13%)

  Fly     9 LLVAFATLLLWDFLWRRRGNGILPGP----------RPLPFLGNLLMYRGLDPEQIMDFVKKNQR 63
            ||:|.|..|...:|:|.....::..|          .|:||||:.:.: |..|   ::|::....
Mouse    30 LLIACAFTLSLVYLFRLAVGHMVQLPAGAKSPPHIYSPIPFLGHAIAF-GKSP---IEFLENAYE 90

  Fly    64 KYGRLYRVWILHQLAVF--STDPRDIEFVLSSQQHITKNNLY-KLLNCWLGDGLLMSTGRK-WHG 124
            |||.::...::.:...:  .:|...:.| .|..:.:....:| :|.....|.|:....... :..
Mouse    91 KYGPVFSFTMVGKTFTYLLGSDAAALLF-NSKNEDLNAEEVYGRLTTPVFGKGVAYDVPNAIFLE 154

  Fly   125 RRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIF----PVICLTALDIIAETAM 185
            ::|||....:....:|:|.|.::::.   |..||..:. ...|:|    .:|.|||    :....
Mouse   155 QKKIIKSGLNIAHFKQYVPIIEKEAK---EYFQSWGES-GERNVFEALSELIILTA----SHCLH 211

  Fly   186 GTKINAQKNPNLPYVQAVNDVTNILIKRFIH-AWQRVDWIFRLTQPTEAKRQDKAIKVMHDFTEN 249
            |.:|.:|.|..:..:.|..|      ..|.| ||....|   |..|: .:|:|:|.:.:.:....
Mouse   212 GKEIRSQLNEKVAQLYADLD------GGFTHAAWLLPAW---LPLPS-FRRRDRAHREIKNIFYK 266

  Fly   250 IIRERRETLVNNSKETTPEEEVNFLGQKRRMALLDVLLQSTI-DGAPLSDEDIREEVDTFMFEGH 313
            .|::||     .|||  |.|::           |..||.||. ||.||:||:|...:...:..|.
Mouse   267 AIQKRR-----LSKE--PAEDI-----------LQTLLDSTYKDGRPLTDEEISGMLIGLLLAGQ 313

  Fly   314 DTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESLRLHPPV 378
            .|:::..::..:.:::...:|::...|.:.|.||| ..|:|...|.:|..::..|||:|||.||:
Mouse   314 HTSSTTSAWMGFFLAKDKPLQEKCYLEQKAVCGED-LPPLTYDQLKDLNLLDRCIKETLRLRPPI 377

  Fly   379 PMIGRWFAEDVEIRGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERFDADVPQI-HPYAYIPF 442
            ..:.|.......:.|..||.|....:...|..|..:.:....:|.|:|:..|.|.. ..:||:||
Mouse   378 MTMMRMAKTPQTVAGYTIPPGHQVCVSPTVNQRLKDSWAERLDFNPDRYLQDNPASGEKFAYVPF 442

  Fly   443 SAGPRNCIGQKFAMLEMKSTVSKLLRHFE 471
            .||...|:|:.||.:::|:..|.:||.:|
Mouse   443 GAGRHRCVGENFAYVQIKTIWSTMLRLYE 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	106/417 (25%)
Cyp51	NP_064394.2	CYP51-like	88..499	CDD:410668	108/422 (26%)