Protein Alignment Cyp4d2 and Cyp4b1

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_031849.1
• Gene: Cyp4b1 / 13120
• MGIID: 103225
• Length: 511
• Species: Mus musculus
• Alignment Length: 513
• Identity: 178/513 - (34%)
• Similarity: 287/513 - (55%)
• Gaps: 36/513 - (7%)

  Fly     2 LGVVGVLLLVAFATLLLWDFLWRR----RGNGILPGPRPLPFLGNLLMYR---GLDPEQIMDFVK 59
            ||:...::::....|.|...|:||    |.....|||......|:.|..:   |||  :::.:.:
Mouse    13 LGLWASVVILMVTVLKLLSLLFRRQKLARALDSFPGPPKHWLFGHALEIQKTGGLD--KVVTWTE 75

  Fly    60 KNQRKYGRLYRVWILHQLAVFST--DPRDIEFVLSSQQHITKNNLYKLLNCWLGDGLLMSTGRKW 122
                ::...:.:| |.|..||..  :| |....:.|:.......:|.....|:|.|||:..|.||
Mouse    76 ----QFPYAHPLW-LGQFIVFLNIYEP-DYAKAVYSRGDPKAAYVYDFFLQWIGKGLLVLEGPKW 134

  Fly   123 HGRRKIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIAETAMGT 187
            ...||::||.||:.:|:.:|.||.:.:.||:::.:.:|......:||..:...|||.:.:...|.
Mouse   135 FQHRKLLTPGFHYDVLKPYVAIFAESTRVMLDKWEKKASENKSFDIFCDVGHMALDTLMKCTFGK 199

  Fly   188 KINAQKNPNLPYVQAVNDVTNILIKRFIHAWQ-RVDWIFRLTQPTEAKRQDKAIKVMHDFTENII 251
            ..:...:.:..|..||:|:| :|:::.|.::| ..|:|:.||  ...:|..:|.::.||.|:::|
Mouse   200 GDSGLSHSDNSYYLAVSDLT-LLMQQRIDSFQYHNDFIYWLT--PHGRRFLRACQIAHDHTDHVI 261

  Fly   252 RERRETLVNNSKETTPEEEVNFLGQKRRMALLDVLLQSTID-GAPLSDEDIREEVDTFMFEGHDT 315
            |:|:..|.:       |:|...|.::|.:..||:||.:..: |..|||.|:|.||||||||||||
Mouse   262 RQRKAALQD-------EKEQKKLQERRHLDFLDILLGARDESGIKLSDADLRAEVDTFMFEGHDT 319

  Fly   316 TTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESLRLHPPVPM 380
            |||.||:.||.::.:|..|||.::|:|::|| ||.| ....||.::.::...:||..||:||||.
Mouse   320 TTSGISWFLYCMALYPMHQQRCREEVREILG-DRDS-FQWDDLAQMTYLTMCMKECFRLYPPVPQ 382

  Fly   381 IGRWFAEDVE-IRGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERFDAD-VPQIHPYAYIPFS 443
            :.|..::.|. :.|:.:|||:..::.|:.|.|:...:..|:.|.|.||..: :...||:|::|||
Mouse   383 VYRQLSKPVTFVDGRSLPAGSLISLHIYALHRNSAVWPDPEVFDPLRFSPENMTGRHPFAFMPFS 447

  Fly   444 AGPRNCIGQKFAMLEMKSTVSKLLRHFELLPLGPE--PRHSMNIVLRSANGVHLGLKP 499
            |||||||||:|||.|||...:..|..||..| .|.  |.....::|||.||:||.|||
Mouse   448 AGPRNCIGQQFAMNEMKVVTALCLLRFEFSP-DPSKIPIKVPQLILRSKNGIHLYLKP 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	157/436 (36%)
Cyp4b1	NP_031849.1	CYP4B-like	67..501	CDD:410771	160/454 (35%)