Protein Alignment Cyp4d2 and Cyp4a10

DIOPT Version :9

• Sequence 1: NP_001284806.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_034141.3
• Gene: Cyp4a10 / 13117
• MGIID: 88611
• Length: 509
• Species: Mus musculus
• Alignment Length: 500
• Identity: 167/500 - (33%)
• Similarity: 273/500 - (54%)
• Gaps: 22/500 - (4%)

  Fly     4 VVGVLLLVAFATLLLWDFLWRRRGNGILPGPRPLPFLGNLLMYRGLDPEQIMDFVKKNQRKYGRL 68
            |:|:|||:..|........|..:.....|.|....|.|:.......:.::|:..::.....:.|
Mouse    24 VLGLLLLLVKAVQFYLHRQWLLKAFQQFPSPPFHWFFGHEKFKGDQELQEIVSCIENFPSAFPR- 87

  Fly    69 YRVWILHQLAVFSTDPRDIEFVLSSQQHITKNNLYKLLNCWLGDGLLMSTGRKWHGRRKIITPTF 133
               |.....|..:....|...|:..:.....|..|:||..|:|.|||:..|:.|...|:::||.|
Mouse    88 ---WFWGSKAYLTVYDPDYMKVILGRSDPKANGAYRLLAPWIGYGLLLLNGQPWFQHRRMLTPAF 149

  Fly   134 HFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIAETAMGTKINAQKNPNL- 197
            |:.||:.:|:.......:|:::.:..||..:.|.||..|.|..||.:.:.|...|.:.|.:.|.
Mouse   150 HYDILKPYVKNMADSIRLMLDKWERLADQDSSIEIFQHISLMTLDTVMKCAFSHKGSVQVDGNYR 214

  Fly   198 PYVQAVNDVTNILIKRFIHAWQRVDWIFRLTQPTEAKRQDKAIKVMHDFTENIIRERRETLVNNS 262
            .|:||:.|:.|:...|..:.:.:.|.|::|:......:|  |.::.||.|:.:|:.|::.|.:
Mouse   215 TYLQAIGDLNNLFHSRVRNIFHQNDTIYKLSSNGRLAKQ--ACQLAHDHTDGVIKLRKDQLQD-- 275

  Fly   263 KETTPEEEVNFLGQKRRMALLDVLLQSTID-GAPLSDEDIREEVDTFMFEGHDTTTSAISFCLYE 326
                 |.|:..:.:|||:..||:||.:.:: |..:||:|:|.|||||||||||||.|.:|:..|.
Mouse   276 -----EGELEKIKKKRRLDFLDILLFARMENGDSMSDKDLRAEVDTFMFEGHDTTASGVSWIFYA 335

  Fly   327 ISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMENVIKESLRLHPPVPMIGRWFAEDVEI 391
            ::.||:.|||.::|::.:||:.  |.:|...|.::.:....|||:|||:||||.|.|..:..|..
Mouse   336 LATHPDHQQRCREEVQSLLGDG--SSITWDHLDQIPYTTMCIKEALRLYPPVPGIVRELSTSVTF 398

  Fly   392 -RGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERFDADVPQIHPYAYIPFSAGPRNCIGQKFA 455
             .|:.:|.|...|:.|:.|..:|:.:.:|:.|.|.||..|.|: |.::::|||.|.|||||::||
Mouse   399 PDGRSLPKGVQVTLSIYGLHHNPKVWPNPEVFDPSRFAPDSPR-HSHSFLPFSGGARNCIGKQFA 462

  Fly   456 MLEMKSTVSKLLRHFELLPLGPE--PRHSMNIVLRSANGVHLGLK 498
            |.|:|..|:..|..||||| .|.  |.....:||:|.||::|.||
Mouse   463 MSELKVIVALTLLRFELLP-DPTRVPMPLARLVLKSKNGIYLHLK 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_001284806.1	p450	32..495	CDD:278495	157/467 (34%)
Cyp4a10	NP_034141.3	p450	52..503	CDD:278495	157/467 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845104
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.640