Protein Alignment Cyp4d2 and Cyp3a16

DIOPT Version :10

• Sequence 1: NP_525043.1
• Gene: Cyp4d2 / 31192
• FlyBaseID: FBgn0011576
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_031846.2
• Gene: Cyp3a16 / 13114
• MGIID: 106099
• Length: 504
• Species: Mus musculus
• Alignment Length: 532
• Identity: 145/532 - (27%)
• Similarity: 259/532 - (48%)
• Gaps: 85/532 - (15%)

  Fly     8 LLLVAFATLLLWDF------LWRRRGNGILPGPRPLPFLGNLL-MYRGLDPEQIMDFVKKNQRKY 65
            |:|:|...:||:.:      |::::|   :|||:||||||.:| .|:||     ..|..:...||
Mouse    12 LVLLAIILVLLYRYGTCTHGLFKKQG---IPGPKPLPFLGTVLNYYKGL-----WKFDMECYEKY 68

  Fly    66 GRLYRVWILH--QLAVF-STDPRDIEFVLSSQQHITKNNLYKLLNCW-LGDGLLMSTGRKWHGRR 126
            |   :.|.|.  |:.:| .|||..|:.||..:......|........ :...:.::...:|...|
Mouse    69 G---KTWGLFDGQIPLFVITDPETIKNVLVKECFSVFTNRQDFFPVGIMSKSISLAKDEEWKRYR 130

  Fly   127 KIITPTFHFKILEQFVEIFDQQSAVMVEQLQSRADGMTPINIFPVICLTALDIIAETAMGTKINA 191
            .:::|||....|::...:.:|...::|:.|:..|:...|:.:..|:...::|:|..|..|..|::
Mouse   131 ALLSPTFTSGNLKEMFPVIEQYGDILVKYLRQEAEKGKPVAVKDVLGAYSMDVIISTTFGVNIDS 195

  Fly   192 QKNPNLPYVQAVNDVTNILIKRFIHAWQRVDW---------IFRLTQPTEAKRQ-----DKAIKV 242
            ..||..|:|:....|.            |.|:         :|....|......     ..:|:.
Mouse   196 LNNPEDPFVENAKKVL------------RFDYFDPLSLSVALFPFLTPIYEMLNICMFPKDSIEF 248

  Fly   243 MHDFTENIIRERRETLVNNSKETTPEEEVNFLGQKRRMALLDVLLQS------TIDGAPLSDEDI 301
            ...|.:.:...|.:     ||            ||.|:..:.:::::      ......||:.:|
Mouse   249 FKKFVDRMTENRLD-----SK------------QKHRVDFIYLMMEAYNKSKDKDSHKALSEIEI 296

  Fly   302 REEVDTFMFEGHDTTTSAISFCLYEISRHPEVQQRLQQEIRDVLGEDRKSPVTLRDLGELKFMEN 366
            ..:...|:|.|::||:|.:||.:|.::.||::|::||:||.:.|  ..|:|.|...:..:::::.
Mouse   297 TAQSIIFIFAGYETTSSILSFTVYSLATHPDIQKKLQEEIDEAL--PNKAPPTYDTVMAMEYLDM 359

  Fly   367 VIKESLRLHPPVPMIGRWFAEDVEIRGKHIPAGTNFTMGIFVLLRDPEYFESPDEFRPERFDAD- 430
            |:.|:|||:|....:.|...:||||.|.:||.|:...:..:||..||:::..|:||:||||..:
Mouse   360 VLNETLRLYPITNRLQRVCKKDVEINGIYIPKGSTVIIPSYVLHHDPQHWPEPEEFQPERFSKEN 424

  Fly   431 VPQIHPYAYIPFSAGPRNCIGQKFAMLEMKSTVSKLLRHFEL-------LPLGPEPRHSMNIVLR 488
            ...|.||.|:||..|||||||.:||::.||..:.|:|::|..       :||    :.|..::|:
Mouse   425 KGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALIKVLQNFSFQPCKETQIPL----KLSRELLLQ 485

  Fly   489 SANGVHLGLKPR 500
            ....:.|.:.||
Mouse   486 PVKPIVLKVVPR 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d2	NP_525043.1	CYP4	66..495	CDD:410721	119/460 (26%)
Cyp3a16	NP_031846.2	CYP3A	67..493	CDD:410743	121/463 (26%)